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Meds, Medical Conditions, and Treatment >> Prescription drug discussion

Thanatopium
Journeyman


Reged: 04/22/04
Posts: 99
Loc: The Howling Wastes
Re: Oxycodone
      08/07/04 08:34 AM

Pulverizing it will make it an instant release med. Simply breaking it, as stated above will only increase the speed odf release by the amount of the surface area that has been generated by the break. The polymerized materials that comprise the matrix that makes these pill time released bind the drug well, and are only slowly dissolved as they pass through the GI tract. A pill cut in half has an increased surface area, but it is not increased by that much. A powdered pill is effectively an IR.

On a side note, there is a new formulation that just got patented that will include an opiate antagonist in the mix, that is encapsulated in an insoluble matrix, so if the pill is not crushed, the antagonist will not be released, and the XR version of the medication will work as normal.

If the pill is crushed, the antagonis is exposed to the GI tract, and will counteract the effects of the opiate medication, making current trends of abuse useless, that is, until someone chemhacks it and figures out how to bypass this measure..

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Entire topic
Subject Posted by Posted on
* Oxycodone lgriffincsa 10/13/03 11:28 AM
. * * Re: Oxycodone snork22   11/17/04 12:01 PM
. * * Re: Oxycodone leap   01/08/05 08:38 AM
. * * Re: Oxycodone daddyj   03/18/05 02:50 PM
. * * Re: Oxycodone trixxie   03/20/05 03:09 PM
. * * Re: Oxycodone Chimingin   02/04/05 12:00 PM
. * * Re: Oxycodone Listvoer   02/04/05 08:14 PM
. * * Re: Oxycodone jenerator   02/05/05 12:19 AM
. * * Re: Oxycodone Chimingin   02/05/05 08:01 AM
. * * Re: Oxycodone jenerator   02/07/05 11:42 AM
. * * Re: Oxycodone Chimingin   02/07/05 12:52 PM
. * * Re: Oxycodone astrophel2   01/09/05 07:11 PM
. * * Re: Oxycodone overrx   02/02/05 01:21 PM
. * * Re: Oxycodone jenerator   02/01/05 12:16 PM
. * * Re: Oxycodone jenerator   02/02/05 07:18 PM
. * * Re: Oxycodone infliksta   02/02/05 07:38 PM
. * * Re: Oxycodone Bamboo   02/04/05 11:12 AM
. * * Re: Oxycodone rockystuart   02/01/05 03:08 PM
. * Re: Oxycodone jenerator   02/01/05 05:34 PM
. * * Re: Oxycodone edward73   09/13/04 04:18 PM
. * * Re: Oxycodone johng   09/13/04 04:54 PM
. * * Re: Oxycodone d989   09/15/04 08:58 PM
. * * Re: Oxycodone d989   09/15/04 09:01 PM
. * * Re: Oxycodone PJoseph   09/16/04 07:43 AM
. * * Re: Oxycodone daddyj   03/16/05 11:16 AM
. * * Re: Oxycodone d989   09/16/04 02:50 PM
. * * Oxycodone and other drug prices at CVS d989   09/16/04 02:56 PM
. * * Re: Oxycodone PJoseph   09/16/04 11:02 AM
. * * Re: Oxycodone drsinn   09/14/04 08:22 PM
. * * Re: Oxycodone night_shade   10/13/03 12:12 PM
. * * Re: Oxycodone pinky   10/13/03 11:35 AM
. * * Re: Oxycodone lgriffincsa   10/13/03 11:54 AM
. * * Re: Oxycodone pinky   10/13/03 12:17 PM
. * * Re: Oxycodone flea   10/13/03 01:26 PM
. * * Re: Oxycodone MetsFan   11/13/04 10:49 PM
. * * Re: Oxycodone bustaboo   04/26/04 08:11 PM
. * * Re: Oxycodone lindasroom   05/27/04 03:31 PM
. * * Re: Oxycodone injoie   05/06/04 10:24 AM
. * * Re: Oxycodone lindasroom   05/27/04 03:30 PM
. * * Re: Oxycodone trixxie   04/26/04 08:58 PM
. * * Re: Oxycodone bustaboo   04/27/04 08:44 AM
. * * Re: Oxycodone dsack   05/01/04 06:56 AM
. * * Re: Oxycodone daisyhess   05/01/04 07:13 AM
. * * Re: Oxycodone night_shade   06/20/04 08:35 AM
. * * Re: Oxycodone Masta_Noid   06/20/04 11:51 AM
. * * Re: Oxycodone sbbear52   07/22/04 08:31 AM
. * * Re: Oxycodone flea   07/23/04 12:28 PM
. * * Re: Oxycodone crc102400   07/23/04 12:35 PM
. * * Re: Oxycodone Morphone   05/01/04 08:54 AM
. * * Re: Oxycodone rockystuart   05/01/04 11:28 AM
. * * Re: Oxycodone daddyj   08/06/04 02:07 PM
. * * Re: Oxycodone johng   08/06/04 06:32 PM
. * * Re: Oxycodone Thanatopium   08/07/04 08:34 AM
. * * Re: Oxycodone JBRONCFAN   09/07/04 08:40 PM
. * * Re: Oxycodone Stardog   09/07/04 09:19 PM
. * * Re: Oxycodone JBRONCFAN   09/08/04 12:55 PM
. * * Re: Oxycodone pecan   10/07/04 11:42 AM
. * * Re: Oxycodone DonBarba   09/08/04 01:17 PM
. * * Re: Oxycodone efffbeee   09/08/04 02:02 PM
. * * Re: Oxycodone JBRONCFAN   09/08/04 04:18 PM
. * * Re: Oxycodone Stardog   09/08/04 04:26 PM
. * * Re: Oxycodone trixxie   09/09/04 07:54 PM
. * * Re: Oxycodone JBRONCFAN   09/09/04 11:44 PM
. * * Re: Oxycodone daddyj   03/16/05 11:16 AM
. * * Re: Oxycodone prettyday   09/10/04 02:17 AM
. * * Re: Oxycodone Pickledoo   09/10/04 07:30 AM
. * * Re: Oxycodone trixxie   09/10/04 08:26 AM
. * * Re: Oxycodone DonBarba   09/08/04 03:23 PM
. * * Re: Oxycodone Listvoer   09/07/04 09:02 PM
. * * Re: Oxycodone JBRONCFAN   09/21/04 10:00 PM
. * * Re: Oxycodone rockystuart   09/22/04 02:01 PM
. * * Re: Oxycodone axe   09/25/04 11:13 AM
. * * Re: Oxycodone Deitrus   10/07/04 10:41 AM
. * * Re: Oxycodone penny67   10/08/04 04:30 PM
. * * Re: Oxycodone Listvoer   10/15/04 07:07 AM
. * * Re: Oxycodone penny67   10/15/04 04:47 PM
. * * Re: Oxycodone pecan   10/15/04 08:44 PM
. * Re: Oxycodone Eeyore27   10/08/04 01:02 AM
. * * Re: Oxycodone johng   10/07/04 11:42 AM
. * * Re: Oxycodone jsumner   09/22/04 06:43 AM
. * * Re: Oxycodone Stardog   09/07/04 09:11 PM
. * * Re: Oxycodone pecan   09/15/04 09:23 PM
. * * Re: Oxycodone Listvoer   09/15/04 10:24 PM
. * * Re: Oxycodone jbone   08/11/04 10:38 PM
. * * Re: Oxycodone nunia720   10/15/04 03:22 AM
. * * Re: Oxycodone daddyj   08/21/04 10:42 AM
. * * Re: Oxycodone Listvoer   08/21/04 11:50 AM
. * * Re: Oxycodone omine   08/12/04 10:36 AM
. * * Re: Oxycodone rooster69   03/06/04 12:48 PM

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