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I also read on the other forum taking mass amounts of grapefruit juice has the same effect of tagament.
It's "Tagamet", not "Tagament". If you spell it incorrectly, and almost everyone does, it doesn't come up when a person who is able to spell tries to do some research on it. It's gotten to be so prevalent that I had to say something. It's not personal, and it's not just you, but about 50% or more posters spell it "Tagement" and people miss out on a lot of info.
Grapefruit juice inhbits CYP3A4, and Tagamet does, too. But Tagamet also inhibits CYP2D6, and hydro gets turned into Dilaudid in smallish (10-15%) by CYP2D6. But hydro is made inactive by CYP3A4, so you have to weight the two against each other. I drink grapefruit juice.
Grapefruit juice from concentrate is better because the skin is used, which has CYP3A4 inhibiting proteins, while more fresh grapefruit juice does not.
I don't know about Ruby Red, but I wouldn't drink it.
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