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500 mg is 1/2 of 1 g. In other words, there are 2 500 mg's in each gram.
So, in order to make 10-15 grams, you need 20-30 pills.
In order to make 25 grams, you need 50 pills.
Sounds high, but some people do it everyday without NAC or any extraction- extremely dangerous in the long-term. Just because you're still alive doesn't mean your liver is in good shape; APAP toxicity is one of those things where you can be asymptomatic until it's too late.
If you ever have excessive nausea and excessive fatigue (more so than what opiates normally cause), combined with upper right quadrant pain- get to an ER ASAP. If you have NAC, take some before you leave. Also keep in mind that not having these symptoms doesn't mean you're ok- for some people, they'll never experience any symptoms from APAP toxicity until it's waaaay too late.