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Yes, NAC = N-Acetyl-l-Cysteine. Mucomyst/Mucosil are the prescription drug name for it, yet it's also available in health food store/GNC to take as a "dietary supplement."
Neither NAC nor any of the drug/substances mentioned here would affect the hydro, so don't worry, you will still get the same high/pain relief you got before. The only thing being affected here is the damage from APAP.
The end result of taking NAC is more natural glutathione, more effective glutathione, and NAC's metabolites can substitute for glutathione in that they bind to NAPQI, the toxic metabolite that is what is actually damaging from APAP overdose. So why not just take glutathione? Some people do, but NAC is more effective and better abosrbed orally (compared to the others).