M4A3
Journeyman
Reged: 12/16/03
Posts: 83
Loc: MD,DE, PA
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I have been taking Hydro and OxyCodone for the past year.
I figured to save on money a little bit I ordered some Codeine / Paracetamol or "ProCo" 15/500mg.
Now, I take my Oxy as normal as I used to. I am not stopping them right now, so I know the symptoms can only come from when I take the ProCo.
I get really bad cramps, gas and sometimes slight runs.
Anyone know why? These ProCo's came from Thailand if that helps.
I hope I didn't pay $50 just for some pills that make me sick!
Also, is Paracetamol 500mg = to 500mg of Acetaminophen?
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manoman
Journeyman
Reged: 12/29/03
Posts: 54
Loc: Warm part of the Sun
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Possibly the codeine has negative interaction with one or more of your other meds? If you review the contraindications for codeine you will note they are plentiful. I would strongly suggest reading up on codeine interactions further, to ensure that it is not conflicting with something else you're using.
Here's what WebMD says:
What other drugs will affect codeine?
Do not take codeine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result.
The most serious interactions affecting codeine are with those drugs that also cause sedation. The following drugs may lead to dangerous sedation if taken with codeine:
· antihistamines such as brompheniramine (Dimetane, Bromfed, others), diphenhydramine (Benadryl, Nytol, Compoz, others), chlorpheniramine (Chlor-Trimeton, Teldrin, others), and others;
· tricyclic antidepressants, such as amitriptyline (Elavil) and doxepin (Sinequan), and serotonin reuptake inhibitors such as fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil);
· other commonly used antidepressants, including amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil);
· anticholinergics such as belladonna (Donnatal), clidinium (Quarzan), dicyclomine (Bentyl, Antispas), hyoscyamine (Levsin, Anaspaz), ipratropium (Atrovent), propantheline (Pro-Banthine), and scopolamine (Transderm-Scop);
· phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Prolixin), thioridazine (Mellaril), and prochlorperazine (Compazine); and
· tranquilizers and sedatives such as phenobarbital (Solfoton, Luminal), amobarbital (Amytal), secobarbital (Seconal), alprazolam (Xanax), diazepam (Valium), lorazepam (Ativan), flurazepam (Prosom), and temazepam (Restoril).
Do not take any of the drugs listed above without the approval of your doctor.
Drugs other than those listed here may also interact with codeine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
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potatoboy99
Permanent Fixture
Reged: 02/04/03
Posts: 1198
Loc: Deep North (East)
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I'm not sure about the exact equivalencies, but 15mg of codeine is pretty lame if you are used to hydro and OC.
I don't know the CoPro product you are using, but I use a 30mg codeine-only product from time to time (Codeisan), and I need to take at least 3 to get any relief at all. I take the codeisan along with some alka seltser, or a couple of tylenol.
Normally I take norco 10/325 two or three times a day, and boy there is no comparison between codeine and hydrocodone. Possibly you are taking so many tabs that all that extra APAPis killing your stomache? Personally I react very badly to Vicodin or even 10/500's, including nausea and cramps. APAP is tough on the stomache.
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M4A3
Journeyman
Reged: 12/16/03
Posts: 83
Loc: MD,DE, PA
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Nope,
Im not taking any other meds except for the Oxycodone.
Also, when I take these Pro/Co's. I am only taking 2 of them.
That means 30mg's of Codeine and 1000 Mg's of Paracetamol
I sure wish I knew what the hell was going on.
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potatoboy99
Permanent Fixture
Reged: 02/04/03
Posts: 1198
Loc: Deep North (East)
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If you weren't taking the OC I would suggest you could be suffering mild withdrawl symptoms, as the 30mg of codeine is not going to put a dent in your opiate tolerance.
Are you taking the ProCo alternating with the OC, or on top of? And if you are taking it on top of the OC, what in the world for?
OC knocks me on my you-know-what, I can't imagine feeling the need to supplement OC with something as comparatively mild as 30mg of codeine. But that's just me.
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M4A3
Journeyman
Reged: 12/16/03
Posts: 83
Loc: MD,DE, PA
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Im taking the Oxy's as normal. No more no less.
So I highly doubt its withdrawal
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night_shade
Threadhead
Reged: 08/26/03
Posts: 907
Loc: The State of Hockey
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Paracetamol is the European equivalent to acetaminophen. Weights and measures equal.
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Never underestimate the predictability of stupidity.
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potatoboy99
Permanent Fixture
Reged: 02/04/03
Posts: 1198
Loc: Deep North (East)
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Quote:
Im taking the Oxy's as normal. No more no less.
So I highly doubt its withdrawal
Just my two cents (again), but I have to say, if I was taking Oxycodone as prescribed, I would feel very little need for codeine on top of it.
What is it you want the codeine to be doing, that the Oxy is not doing? The OC should be dealing with the pain issues all by itself.
Anyway I have personally never had a reaction like that to a small amount of codeine or APAP, alone or in combination.
Good Luck, hope you're feeling better!
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actonbell
Journeyman
Reged: 09/08/03
Posts: 82
Loc: Oklahoma
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codiene can be really hard on your stomach. Codiene on an empty stomach often causes nausea and vomiting/pain. Once in my misbegotten youth, a freind gave me a tylenol # 3 for a headache. I took it with a cup of coffee. Got to work and was having terrible stomach pains. Called the ER told the doc what was happening and he said and I quote "go take some malaox and don't do anything that stupid again. Allways eat food before taking codiene". I slunk off to the office got some malox and was fine as soon as it hit my stomach.
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All it takes to fly is to hurl yourself at the ground....and miss.
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magnumopus
Stranger
Reged: 01/14/04
Posts: 2
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Most find codeine a good pain killer and quite fun to take. However, about 7% of people lack a key liver enzyme that converts codeine into morphine in the body, and these unlucky souls find codeine just makes them sick. Coincidentally, the enzyme used by the human body to covert codeine to morphine, CYP2D6, is also one of the 2 liver enzymes that are key to metabolizing dextromethorphan. Without the proper CYP2D6 gene, almost no codeine is converted to morphine, which makes for a hellish, unpleasant experience.
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mrscoach
Journeyman
Reged: 07/29/02
Posts: 82
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I used to take tylenol 3 with no problems at all. Then it was like suddenly one day, I became allergic to it or something. I would take my usualy dose of 2 pills, and within 20 minutes would have the worst stomach pain, like cramps. It felt like a gallstone attack, except that I had had my gallbladder removed a year earlier. So for some reason, I had become intolerant to codeine, but hydro still works fine for me (with the exception of the occasional rebound headache - I hate those things!).
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"I'm not tense - just terribly, terribly alert."
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potatoboy99
Permanent Fixture
Reged: 02/04/03
Posts: 1198
Loc: Deep North (East)
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Quote:
about 7% of people lack a key liver enzyme that converts codeine into morphine in the body, and these unlucky souls find codeine just makes them sick.
I didn't know that. So I guess someone could be fine on synthetic opioids like hydro and ocycodone, and be unable to process and actual opiate like codeine.
You learn something new every day around here! Thanks.
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M4A3
Journeyman
Reged: 12/16/03
Posts: 83
Loc: MD,DE, PA
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I would also like to thank all who have helped me in this thread.
I figured, I would give this batch one last shot.
I took one of the pills. Had the same cramps and trots...
After being sick I took a shower. Got out of the shower and it looked like Mike Tyson just punched me in both eyes!
I had very very dark circles under my eyes and my pupils were pretty large.
I really have no idea why this is happening.
Before I went on Oxy's, I was on T3 and never, ever anything like this happened.
Just so anyone wants to know..
The pills are the size of a 5/325 Hydro pill and the same shape.
Also, on the top it reads "P-CO 15" one thing that makes these stand out is they are a baby blue in color.
They were bought from a Thailand op. I wont give the web ID of that place because I don't think that's right to do on a public forum. I am sure that this place would give out bad stuff on purpose either.
I have taken plenty of Codeine before, and never had this reaction.
I truly think this is a very bad batch.
I will write the OP I got them from tonight to let them now.
I am really more upset in the fact I don't have anymore OXY's No more Insurance so I cant go back to my Doc.
That meansd I have nothing for my Best if kept off the board pain. Its about 5F degrees out and with it being that cold my pain gets much much worse! If anyone has ideas about how I can get the needed meds I need fast. Please PM me or post here.
I hate to go two weeks with nothing. I will probably lose my job since I cant work in that kind of pain.
Thanks
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bhamdave
Threadhead
Reged: 01/11/02
Posts: 949
Loc: U.S.A.
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Quote:
"The pills are the size of a 5/325 Hydro pill and the same shape.
Also, on the top it reads "P-CO 15" one thing that makes these stand out is they are a baby blue in color.
They were bought from a Thailand op. I wont give the web ID of that place because I don't think that's right to do on a public forum. I am sure that this place would give out bad stuff on purpose either."
Yes, this is a public forum, yes we do have other sites listed here, yes some of them are from Thailand, if we don't know the op it is very difficult to help with this.
Is the OP listed on this site? We just need more info.
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AIDS
It's not YOUR problem (I hope that)
It's not MY problem (I know that)
But it is still OUR problem and WE know that!
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M4A3
Journeyman
Reged: 12/16/03
Posts: 83
Loc: MD,DE, PA
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Quote:
Quote:
Is the OP listed on this site? We just need more info.
Well, since you have 836 posts, and you think its ok..
I bought them from 247-drugstore.com
Its the product:
"Paramed, Codeine/Paracetamol 15/ 500mg, 50 tab "
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bhamdave
Threadhead
Reged: 01/11/02
Posts: 949
Loc: U.S.A.
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Thank you,
Also named: Codicet, Codigesic, Paramed
Don't know the reason it should be making you sick.
The company has a good reputation.
Sometimes the combination of codeine and acet, can't make me sick, but not often.
Try if you can and not take any for a couple of days just to let it get out of your system.
In the meantime check out : Who Offers It / How Much / With Updates/ Codeine for other places to purchase, you may also find a US Consult site to meet your needs.
Bhamdave
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AIDS
It's not YOUR problem (I hope that)
It's not MY problem (I know that)
But it is still OUR problem and WE know that!
Edited by bhamdave (01/19/04 09:28 PM)
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PrivateRealm
Threadhead
Reged: 03/18/03
Posts: 879
Loc: usa
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Mre than likely it is the codeine, though weak, and comparatively the huge amount of APAP that you are taking that is making your stomach upset.
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KeriAnne~~~
"Life is not measured by the number of breaths we take - but by the moments that take our breath away."
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potatoboy99
Permanent Fixture
Reged: 02/04/03
Posts: 1198
Loc: Deep North (East)
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Man, what a drag. I am so sorry this is happening to you.
What you probably need to do is do a consult for hydro right away, maybe from NWW or Fedexmeds or Medsviaweb, all of whom require records of some kind, but all three of whom are known to be speedy when necessary with the first fill.
I have had overnight delivery from both NWW and Medsviaweb, during the past year, meds in hand the morning after consult. (Others have had different experiences of course.)
Good luck, it's an awful thing when our medicine turns against us!
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voyager
Old Hand
Reged: 04/17/03
Posts: 413
Loc: United States Virgin Islands
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Codiene has as a classic side of nausea, stomach cramps etc. I suspect that you are just intolerant to codiene and therefore it is making you sick.
I really think it is just that simple.
Good luck.
voyager
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M4A3
Journeyman
Reged: 12/16/03
Posts: 83
Loc: MD,DE, PA
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Well, I am sure now that it was and batch.
I ordered codsiesan and the stuff works fine with no cramps at all.
Just thought I would update you!
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sjm
Stranger
Reged: 11/11/03
Posts: 18
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Sorry that I did not see your post sooner. I had a similar experience several years back with a Far Eastern supplier of paracetamol and codeine. It made me sick. I gagged, sometimes vomited, and often had diarrhea. When I stopped taking them, the symptoms subsided. So in my case, I wasted $50 or so. For me, it wasn't the codeine, I later added (from the US) Tylenol III with no ill effects.
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