BlackCat
Old Hand
Reged: 09/22/03
Posts: 403
Loc: Bed
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I've read that 4,000 mg of APAP is the daily maximum for short durations and just read another post that said 2,600 mg of APAP is the daily maximum for extended periods - like chronic pain patients taking hydro/APAP daily!! Everyone here seems to know that exceeding these limits causes increased risk of liver damage.
How do you know if you have or if you are developing liver damage from taking too much APAP over an extended period?
What are signs and symptoms to look for?
When I get my annual physical with blood work now I always ask for the special "LFT (liver functioning test) blood panel" that gives me numbers for two liver tests: AST and ALT. If they are within the normal range (AST
In terms of prevention, I try to keep my APAP intake as low as possible and take norco 10/325s. I also don't touch alcohol and started taking NAC daily to help metabolize the APAP and also mitigate the risk of liver damage.
BOTTOM LINE: How do I tell (symptoms) if I have or am developing liver damage from excess APAP consumption?
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voyager
Old Hand
Reged: 04/17/03
Posts: 413
Loc: United States Virgin Islands
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If your lab results are normal then i wouldn't worry about it. I would keep my apap intake within range and check my liver functions periodically (every 3 months) if you are close to the max intake of APAP.
Otherwise your liver regenerates itself and i wouldn't worry about it.
voyager
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AngelRat
Member
Reged: 04/14/03
Posts: 175
Loc: CA
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Any pain pill containing APAP should be pre-fortified with NAC to begin with. I see no reason why this could not be done.
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I'm floating around like a chicken with my legs cut off. I am the poultrygeist. Goo goo g' joob, and a cockadoodle BOO to you dude.
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BlackCat
Old Hand
Reged: 09/22/03
Posts: 403
Loc: Bed
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I agree in principle, but the extra NAC needed to help would probably make the darn pills too big or make you have to take alot more little APAP/NAC ones and baffle Joe and Joan America.
I take 1,000 mgs of NAC with my hydros. which are two pretty large 500 mg capsules.
Anway, back to topic:
Symptoms?? - How does one know if their liver is getting damaged from excess APAP if they exceed the 4,000 mg per day recommended limit? Do you turn yellow, pee blue, poop rainbows, feel stomach pain, etc.?
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Queeny
Banned for soliciting
Reged: 08/16/03
Posts: 28
Loc: West Coast
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Well, I for one, have had liver damage, but not from hydro, or apap.... my doc put me on something called "methotrexate" which is for rheumatory arthritis, and it works, but as they slowly increased my doses, my liver becamed damaged..... and there were some symptoms, I just didn't know that they were related to each other, one of the symptoms is nausea towards the evening, I would be hungry towards dinner time, but when I started to eat, I became sick to my stomache, at the time I didn't know that it was because my liver test (SGOT) was at 186 and the ALT (SGPT) was at 69, and here is the normal range for liver function test.
Liver Test SGOT - 10 to 40 = normal range
ALT (SGPT) - 0 to 40 = normal range
Now anything higher means that your liver in inflammed, but it does take ALOT of apap to make your liver to get inflammed, cause I've taken alot of hydro in a day, and doesn't even come close to what the methotrexate did.
Honestly.... and I definatly do not recommend this.... I've taken up to 18 (5/500) hydros in a day, and that was when I herniated two discs in my back and the pain was just totally un-bearable!!! So if you multiply 500 x's 18.... OMG!!! I've never really done the math before, that means that I had taken 9000mg of apap that day!!!! And this was after my liver was inflammed the first time, and the liver test I did after that was normal so it didn't effect my liver at all, even after it had already been inflammed once, but since they have taken me off of methotrexate, but I still have to do monthly blood work ups, and since I've been off of methotrexate, my liver has not since flared up.
But you also have to realize that every person is different, as some can take high doses of methotrexate and never have a problem, I was on low doses of it when it hurt my liver, and I was not taking hydros at the time, so I knew it wasn't the apap that caused it. (I know some were thinking that )
There is also a supplement out called "milk thistle" which helps inprove liver function, I've never taken it, but many have, if you do a search, I'm sure you can read more about it, and it's available in a local health food store.
If anyone needs the normal ranges of blood work ups for liver and kidney functions, I do have them, as I request them to be mailed to me after every test. So if anyone is interested I will be happy to post them.
Thanks
Q 
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Another username / alias used by "tammylynn" to bother...
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AngelRat
Member
Reged: 04/14/03
Posts: 175
Loc: CA
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Perhaps if they stomp it with a multi-ton hydraulic press it will render it small enough. Perhaps 1,000mg is overkill. I don't know, as I've yet to actually take any NAC. Does it have it's own dangers, or is it a completely harmless good idea?
From what I've read (forgot where I read it) symptoms from damage can show up 24 - 48 hours after it occurs. Yellow skin, yellow eyes, brown tongue, pain where your liver would be, and I hate to say it, but death I suppose. Before this stage, symptoms may just be nausea and sweating etc. which, for me, would be hard to go by because I seem to sweat when I take more than one or one too frequently anyway, and the nausea seems to go with that territory as well. I myself would appreciate a comprehensive checklist that someone could point to out there on the web. Until then, I'll continue to jot down every pill I take and subsequently note when 6 hours has passed (not that I always wait that long).
Nobody rely on anything I have to say about this - check it out and do so thoroughly your own selves, please (must cover my buttocks here).
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I'm floating around like a chicken with my legs cut off. I am the poultrygeist. Goo goo g' joob, and a cockadoodle BOO to you dude.
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AngelRat
Member
Reged: 04/14/03
Posts: 175
Loc: CA
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I think also there is a difference between someone who would try to take 18 in one day without gradually working up to that amount. If the intake is gradually increased, over time, I do believe that the liver learns to ramp up production of that particular compensatory chemical to handle it, whereas if one where to try it suddenly, the liver would run out of it right then and there, resulting in damage. Also, consider someone who worked their way up as described, stopped consumption for a period of time (weeks or months) and then tried to pick up where they left off, quantity wise, not realizing the liver may have to work itself back up to that level gradually again. Boom - damage. It's just a "theory". Nobody should take comfort in it but should verify everything through proper channels (and I am certainly not one of those).
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I'm floating around like a chicken with my legs cut off. I am the poultrygeist. Goo goo g' joob, and a cockadoodle BOO to you dude.
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johng
Board Addict
Reged: 02/13/03
Posts: 354
Loc: great lakes
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a good sign is pain. my brother was on a choleleteral lowering drug and caused damage to his liver. his first sign was terrible back pain in the area of the right shoulder blade. then it begain to hurt in the liver area. another common sign is pain referd to the right shoulder. as these occure the other signs will begin yellow of the skin brown pee and so forth. I read in the PDR that doses of apap in the 7000 mg rang have rarely caused failure. but if you continully push the limit one day the liver will not 'bounce back'
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Ask and it will be given to you Matthew 7:7
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potatoboy99
Permanent Fixture
Reged: 02/04/03
Posts: 1200
Loc: Deep North (East)
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As usual I'm confused. Is it definitive that 2,600 mg per day of APAP is the maximum for extended use? Or is that your ballpark figure? This is of real concern to a lot of us here.
Personally I'm also on Norco 10/325's, usually 3 or 4 a day, which puts me at 975 or 1300 mg per day, or half the maximum. I'm certainly concerned that tolerance could start pushing up the # of Norco I need daily, although so far I'm ok. I have the ocasional good day where I only need one or two to get through the day.
And I'm scared to death of the deadly alcohol/APAP combo. I don't think it can be emphasized strongly enough how dangerous it is to drink on top of hydro/APAP or tylenol compounds. I have several friends battling liver disease, some as a result of chronic alcoholism, and others due to hepatitis C. Believe me you don't want to be in their shoes if you can avoid it.
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Box_of_Rain
Banned=more than one account
Reged: 09/28/03
Posts: 111
Loc: Pacific Northwest
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I'd like to know also!
I just took 5 stupid piece of dung Darvocets, (I am dying with this tooth pain) and that adds up to 3250mg of APAP all at once. This freaks me out terribly but it's about the only thing I can get without much hassle. [sigh] I am too broke right now to buy from an OP so I need it prescribed so my insurance can pick up the tab (mostly). ARGH, stupid APAP in everything!!!! 
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AngelRat
Member
Reged: 04/14/03
Posts: 175
Loc: CA
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Quote:
As usual I'm confused. Is it definitive that 2,600 mg per day of APAP is the maximum for extended use? Or is that your ballpark figure? This is of real concern to a lot of us here.
That is the figure given at the official Norco website.
http://www.norco-rx.com/acetaminophen.htm
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I'm floating around like a chicken with my legs cut off. I am the poultrygeist. Goo goo g' joob, and a cockadoodle BOO to you dude.
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hooru
Stranger
Reged: 01/04/02
Posts: 22
Loc: Texas
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The best thing that I have found during my extensive research on liver function is Alpha Lipoic Acid. Usually you will hear about Milk Thistle, but this stuff blows Milk Thistle away. My sister is an insulin independent diabetic and had a rock come out from under the lawn mower and hit her on her leg creating a big red sore.
Since then, it has been one dermatologist after another for years with no improvement. All the while this red sore is growing bigger and becoming sorer. One Dermatologist even gave her over 20 cortisone shots in the sore with no results. She has also been on multiple creams, all with no help.
I had her start taking 100mg of Alpha Lipoic Acid and within 4 months her sore is lighter in color and doesn't hurt as bad. So now she has upped her dose to 200 mg and we will see what happens.
There has also been a Doctor that saved two lives of individuals that ate bad mushrooms. The other doctors at the hospital said there was nothing that could be done they were too far gone, and left them to die. This doctor researched and found out about Alpha Lipoic Acid and used it on both patients without approval. Both patients lived. But the Doctor that saved their lives was reprimanded. By the was, in case you are not aware of it, eating bad mushrooms kills you by destroying your liver. I would suggest any person taking tylenol regularly take this supplement. It will truly help keep your liver healthy.
Sherrie
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CeeBee
Member
Reged: 08/09/03
Posts: 185
Loc: garden state
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Sherrie, thanks for that great info, where would one look for this supplement? In a drugstore or a health/vitamin store. Thanks, CeeBee 
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hooru
Stranger
Reged: 01/04/02
Posts: 22
Loc: Texas
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You can get it at any health food store, I purchased mine online, then found it at Wal-mart. Be careful there is a large discrepency in price. You should pay no more than $10.00 for 100, 100mg capsules.
I take two capsules in the morning and then dependng on what I have done that day I take 2 more capsules in the evening.
By the way it is the liver that is reponsible for flushing out the fat in our system, so if you are on a diet, I highly reccomend this supplement to help take some of the stress of the liver and increase your weight loss.
Good Luck,
Sherrie
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Tred
Enthusiast
Reged: 10/18/03
Posts: 262
Loc: USA
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Here's my story real quick:
Pinched nerve (cyatic region, lower back) also torn intercostal cartilage in rib cage.. Started meds with an apap level of 3000mg a day. Never went over once... Follow up with PCP and continued on meds for a few more months. Middle of month three started getting dizzy spells, hot flashes, bloodshot eyes, ect. Got very scared and had full bloodwork done. My alt levels came back at 179!!! This whole time I was taking NAC 1200mg a day. I had a very wierd feeling that the cause of my alt levels to rise was directly from the NAC. I don't know why I felt this way, because all informaiton I found said NAC did the exact opposite. I decided to stop taking NAC and lowered my apap use to 2000mg a day. Had bloodwork done one month later and my alt levels are now back down to 45!! So in the end I don't know if it was the apap or NAC?? Either way I've stopped NAC completly and stay under 1000mg apap. I still take the same ammount of meds due to ongoing medical problems, but I've lessened the apap using a certain method. All problems cleared up and feeling 10X better. IMO I would try to always stay under 2000mg apap if your considering using a medication for longer than one month. Long term treatment should always have the least apap possible. You only have one liver and taking medication is not worth risking your life. If you do a search on the web about lowering apap in certain meds, you'll find a method that can help. Good luck and stay safe!!!
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Entertainment Specialist!
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Queeny
Banned for soliciting
Reged: 08/16/03
Posts: 28
Loc: West Coast
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I'm sorry, what is "NAC" is that like milk thistle?
I know that all medications go thru the liver, and so your liver could be inflammed one month and the next it could be fine, I even have a friend, who was on no medication, she had blood work done, and her liver came back at a high number, and her doc sent her back to the lab to have it re-done a couple days later, and her liver test came back normal the second time, so, sometimes the test could come back with a false reading.
It is a very good idea to have blood work done at least once every three months or so, esp. if you take apap, the main problem with taking apap is not to combine it with drinking, I don't drink at all, I just never liked it, which is a good thing, but even plain Tylenol says that it could cause liver damage if you drink and take it.
So, if anyone takes apap, they should request to have the liver blood work ups at least once every 2 to 3 months, just to be safe.
I don't think any Doctor would refuse that request. 
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Another username / alias used by "tammylynn" to bother...
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Sky_Queen
Fly Girl
Reged: 12/03/02
Posts: 1962
Loc: Texas
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Ok, I don't understand this table on this link. When I'm looking at consumption of APAP per day, I think of it in terms of the amount in the hydro tab - for instance I take the 10/500's, three a day. I look at that like 1500 of APAP per day. Can somebody please explain what this table means in the terms they are speaking?
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LumbarSpasm
Silent Chaos
Reged: 05/07/02
Posts: 1538
Loc: USA
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Other signs of liver problems are itching and thin clay colored (light colored)or stools. The gradual discoloration of your skin and eyes may be something you don't notice... but other people might. And orangish colored urine is another sign.
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LumbarSpasm
Or just a pain in the butt?!
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antique
Banned
Reged: 09/01/03
Posts: 215
Loc: east coast
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http://www.medicinenet.com/Tylenol_Liver_Damage/page1.htm
What happens to a person with acetaminophen-induced liver damage?
Three clinical stages (phases) of acetaminophen-induced liver injury have been described. During the first phase, that is, the initial 12 to 24 hours or so after ingestion, the patient experiences nausea and vomiting. For the next perhaps 12 to 24 hours, which is the second phase or the so-called inactive (latent) phase, the patient feels well. In the third phase, which begins about 48 to as late as 72 hours after the ingestion of acetaminophen, liver blood test abnormalities begin to appear. Most notably, extremely high (abnormal) levels of the liver blood tests, AST and ALT, are common with this type of liver injury. The outcome (prognosis) of the liver injury can be predicted fairly accurately on the basis of the patient's clinical exam and blood tests. For example, at one extreme, if the patient develops severe acid buildup in the blood, kidney failure, bleeding disorders, or coma, then death is almost certain. Only a liver transplant can possibly save such a patient.
What should be done if acetaminophen toxicity is suspected?
A physician should evaluate the individual immediately. Remember that bringing the bottles of acetaminophen and all of the person's other medications to the emergency room is always useful. The risk that an acetaminophen overdose will cause liver injury correlates with the blood level of acetaminophen relative to the time the drug was taken. Physicians, therefore, are able to estimate the patient's probability of developing liver injury after an overdose. To make this determination, they obtain the patient's history of acetaminophen ingestion and measure the blood level of the drug. With this information, the doctor then can refer to a table (nomogram) that provides an estimate of the risk of developing liver injury. The accuracy of this estimate, however, depends on the reliability of the time of ingestion and whether the acetaminophen was taken over a period of time or all at once.
With suspected acetaminophen overdose, the doctors usually will pump (gavage) the patient's stomach to remove pill fragments. In reality, many individuals who overdose with acetaminophen in a suicide attempt will have taken other pills in addition. Some doctors, therefore, will consider treating the patient with activated charcoal, which binds (and thereby inactivates) many medications. However, this treatment is controversial because of a concern that the activated charcoal may also bind the antidote for acetaminophen overdose.
Patients who are thought to be at a high-risk or even only at a possible risk of developing acetaminophen liver injury should be given the antidote, N-acetyl cystiene (Mucomyst) orally (or intravenously in Europe). This drug works by indirectly replenishing glutathione. The glutathione, as you recall, detoxifies the toxic metabolite of the acetaminophen. The N-acetyl cystiene is most effective when administered within 12 to 16 hours after the acetaminophen was taken. Most physicians however, will administer N-acetyl cystiene even if the patient is first seen beyond this 16 hour period. Thus, a British study showed that patients already with liver failure who then received the N-acetyl cystiene were more likely to survive than patients who did not receive the antidote. Moreover, the survival occurred in these patients regardless of the time of initial administration of N-acetyl cystiene. Finally, people who recover from acetaminophen-induced liver damage are left, fortunately, with no residual or ongoing (chronic) liver disease.
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antique
Banned
Reged: 09/01/03
Posts: 215
Loc: east coast
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http://www.ecureme.com/emyhealth/data/Acetominophen_Overdose.asp
Initially often only nausea/vomiting/sweating, then no other symptoms for 24 hours.
At 24-48 hours, liver damage occurs, which can lead to right upper quadrant abdominal pain, jaundice (yellow skin) or icterus (yellow eyes), confusion, coma, kidney failure, and death.
http://ecureme.healthology.com/focus_article.asp?f=xmlpressfeed&c=liver_transplantation
When is a liver transplant necessary?
MICHAEL ABECASSIS, MD: There are a couple situations that mandate a liver transplant. First, there are people with no history of liver disease who suddenly experience acute liver failure. There are multiple causes for this type of failure, including viruses or Tylenol overdoses, and these people usually require transplant urgently.
The second group of patients who require transplants are those with chronic liver disease, which can be caused by viral hepatitis, hepatitis-B, hepatitis-C, cirrhosis, alcohol, cholestatic diseases and sclerosing cholangitis. There are pages and pages of possible causes of chronic liver disease. These people develop chronic liver disease and then develop complications, which might include bleeding varices (abnormally swollen blood vessels), fluid buildup in the abdomen, or liver cancer.
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antique
Banned
Reged: 09/01/03
Posts: 215
Loc: east coast
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http://www.ucdmc.ucdavis.edu/pulse/scripts/01_02/painkillers_and_liver_dmg.html
Painkillers and Liver Damage
Over-the-counter pain medication can be such a blessing when we're not feeling great. It's so easy to just take a pill and feel a whole lot better. But, medicine that's easy to get and easy to take can also have an unexpected effect on our liver.
Nurse
"Are you in any pain at all today?"
Beverlee Norene
"No, not today."
A YEAR AGO, BEVERLEE NORENE WAS IN THE EMERGENCY ROOM AT UC DAVIS MEDICAL CENTER. SHE WAS IN A COMA, AND SHE WAS DANGEROUSLY CLOSE TO DEATH.
Dr. John McVicar/Liver Transplant Surgeon
"When Beverlee Norene came into the hospital we weren't quite sure exactly what was wrong with her although we did eventually find out that she probably took too much Tylenol."
Norene
"I was taking Tylenol cold medicine, Tylenol to sleep, Tylenol for headaches. We just don't realize that what's in our medicine chest could kill us."
OVER-THE-COUNTER PAIN MEDICATION WAS A BIG PART OF THE PROBLEM. BEVERLEE'S LIVER HAD BEEN DAMAGED BEYOND REPAIR. SHE EVENTUALLY HAD A LIVER TRANSPLANT TO SAVE HER LIFE.
Dr. McVicar
"There was almost no liver function left at all."
Dr. McVicar
"Does it hurt when I push on it?"
Norene
"No."
BEVERLEE'S CASE IS EXTREME. BUT LIVER DAMAGE BECAUSE OF OVER-THE-COUNTER PAIN MEDICINE IS NOT UNCOMMON.
Dr. Neville Pimstone/Gastroenterologist
"Fifteen to 30 percent of Americans use pain tablets for chronic pain syndromes, the common ones being rheumatological conditions, headaches, back pain."
TYLENOL IS A TRADE NAME FOR A CHEMICAL COMPOUND CALLED ACETAMINOPHEN. ACETAMINOPHEN IS IN A LOT OF OVER-THE-COUNTER MEDICINES: COLD AND FLU MEDICINES, SLEEP PREPARATIONS, HEADACHE REMEDIES AND MORE. NOW TO UNDERSTAND THE WHOLE PICTURE BETTER, THINK OF YOUR LIVER AS A GIANT DETOX CENTER.
Dr. Pimstone
"Its main function is to take in all the nutrients, all the things that we're exposed to in the environment and to either use it for good purpose or to detoxify it to render it harmless."
THE LIVER GENERALLY DOES A GREAT JOB, BUT TOO MUCH ACETAMINOPHEN CAN OVERWHELM THIS PROCESSING CENTER.
Dr. Pimstone
"Let's say a person in extreme pain takes eight or 10 extra-strength Tylenol a day that's 5 grams a day. That could be enough to overwhelm the liver's defense mechanism."
AND IF YOU ADD ALCOHOL, EVEN A SOCIALLY ACCEPTABLE ONE OR TWO GLASSES OF WINE A DAY, YOU NEED ONLY FOUR EXTRA-STRENGTH TYLENOL OR ACETOMINOPHEN TABLETS A DAY TO CAUSE LIVER DAMAGE. WHAT KIND OF DAMAGE? WELL, THE LIVER DEVELOPS FIBROUS TISSUE WHICH CAN DEVELOP THEN INTO SCAR TISSUE. AND THE SCAR TISSUE CAN LEAD TO CIRRHOSIS OF THE LIVER.
Dr. Pimstone
"A person may have cirrhosis of the liver for 10 or 15 years before there's a danger of liver failure or liver cancer developing, so it's a silent killer."
THE GOOD NEWS IS THAT ONLY A FRACTION OF THE PEOPLE WHO ARE TREATING CHRONIC PAIN WITH TOO MUCH ACETAMINOPHEN WILL ACTUALLY GET INTO TROUBLE. EVEN WITH THE ADDITION OF ALCOHOL, THE CHANCES OF GOING INTO COMPLETE LIVER FAILURE ARE SMALL.
IN BEVERLEE'S CASE, DOCTORS THINK A SERIOUS VIRUS MAY HAVE COMPROMISED HER LIVER, WHICH THEY BELIEVE WAS ALREADY STRESSED BY THE TYLENOL. SHE WAS SO SICK THAT SHE HAS NO MEMORY OF THE DAYS BEFORE HER LIVER TRANSPLANT.
Dr. McVicar
"Good result! I'm very pleased."
SO HOW CAN YOU MAKE SURE YOU DON'T DAMAGE YOUR LIVER WITH PAINKILLERS? HERE ARE SOME THINGS TO KNOW:
THERE ARE THREE CATEGORIES OF OVER-THE-COUNTER PAIN MEDICATONS, WHICH CAN POTENTIALLY CAUSE TROUBLE.
THE FIRST IS ACETAMINOPHEN, AND A WELL-KNOWN BRAND NAME FOR IT IS TYLENOL.
THE SECOND CATEGORY IS ASPIRIN COMPOUNDS. TOO MUCH ASPIRIN CAN CAUSE A TYPE OF LIVER STRESS THAT IS QUICKLY REVERSIBLE. IN YOUNG CHILDREN, ASPIRIN CAN INTERACT WITH THE LIVER TO CAUSE REYE'S SYNDROME, WHICH IS A SERIOUS, POTENTIALLY DEADLY CONDITION.
THE THIRD CATEGORY IS NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, OTHERWISE CALLED NSAIDS. THESE ARE MEDICATIONS LIKE MOTRIN, ADVIL OR IBUPROFEN.
REMEMBER, MOST LIVER DAMAGE FROM OVER-THE-COUNTER PAIN KILLERS COMES FROM USING TOO MUCH.
Norene
"Just because it's over the counter doesn't mean it's healthy for you. People should read the ingredients over the counter and should know what is in them."
Here's some good news... doctors say the liver can actually heal itself if it gets a rest from drug and alcohol overload. And that period of regeneration and recovery can happen quickly sometimes in just a week if serious damage hasn't occurred.
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potatoboy99
Permanent Fixture
Reged: 02/04/03
Posts: 1200
Loc: Deep North (East)
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Thank you for posting the Norco link, angelrat! It's good to see that in black and white. I'm supposing 2.6 grams is 2600mg.....I was never good at math.
And antique, thank you too for posting those links and that cautionary tale. I have a friend who went through something very similar 15 years ago, complete liver failure due to excess Tylenol. It seemed ridiculous at the time to think that something OTC could cause so much damage.
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yawkaw3
Pooh-Bah
Reged: 03/22/03
Posts: 1193
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Not everyone agrees on what is an acceptable amount of APAP. Some will say 2600 mg, some say 4000 mg, etc. The real answer is that it is different for everyone based on your unique body chemistry. But whenever new guidelines from any source come out, they are always lower...
If you take a sufficient amount of NAC (covered in other threads), you will be in good shape. You can throw milk thistle in there too, as well as a multivitamin, but the NAC is the key ingredient here.
-yawkaw
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AngelRat
Member
Reged: 04/14/03
Posts: 175
Loc: CA
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I believe you are looking at it correctly. Basically, they are saying one can take 4 grams of acetaminophen per day for up to 10 days. 4 grams = 4000 milligrams. That's 8 Lortabs at 500mg each, or 12.3 Norcos at 325mg each. Beyond 10 days, it should be lowered to 2.6 grams per day. 2.6 grams = 2600 milligrams. That's 5.2 Lortabs or exactly 8 Norcos (exactly by design).
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I'm floating around like a chicken with my legs cut off. I am the poultrygeist. Goo goo g' joob, and a cockadoodle BOO to you dude.
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BlackCat
Old Hand
Reged: 09/22/03
Posts: 403
Loc: Bed
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Has anyone ever heard of the "4,000 mg rule" varying based on a person's weight? (e.g. a 200lb man can handle more per day vs. a 120lb woman)
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CeeBee
Member
Reged: 08/09/03
Posts: 185
Loc: garden state
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Sherrie, again thanks for the info I appreciate it. 
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asbury02
Stranger
Reged: 10/21/03
Posts: 7
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I am a firm believer in several factors -- 1. take a breather from it and your body is tremendous in it's ability to heal itself
2. always drink allot of water
3. anti oxidants and MILK THISTLE are a big help
4. listen to yourself-- do you fell OK? or are there symptoms that could be liver related? If so take action-- if not always take the holistic precautionary route -positive mental attituse, moderation, etc.
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