537
Threadhead
Reged: 12/08/01
Posts: 766
Loc: west coast CA
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Today, I went in for my second set of epidural injections, but I was not able to actually go through with it. Something happened to me after my IV was put in and I was given Reglan. I started to become very anxious and sick. Very panicked. So, I decided to leave, that I could not go through with it and I had to go home. It was all I could do not to rip the IV out of my arm. The doctor came over to try to talk me out of it by offering to give me anti-anxiety meds, but I declined and he became very rude to me. So I will be going back to my PCP and getting a referral to a new PM doc. Anyway, I was wondering if anyone else has had a bad reaction to Reglan, which is an anti-nausea medicine?
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keystone
Veteran

Reged: 09/05/02
Posts: 586
Loc: Arizona, USA
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Reglan helps get your "GI" tract moving as well. You may have had some gas (we all know gas can feel like death at times) or just some food "backed up" in your system that didn't agree with you. Some people also do occasionally get -the best way I can describe- is almost like a caffeine "high" or "low" the way you want to look at it. Jittery, spacey...etc.
I use Reglan at leat weekly for nausea from migraines. 90% of the time it is fine. The tablets kick in in approx. 30 minutes and last 6-8 hours. The other 10%, I must run to the bathroom or experience some discomfort.
I would honestly say to try it again, I.V. induction may have been too rapid. Perhaps he can give you some pills to take before your visit. The BETTER solution is Zofran. I use Zofran ODT 8MG. (ODT=orally disint. tabs) Best anti-nauseant on the market. (Most expensive though, to.)
Back to your point, Reglan is a widely popular and old drug that's well tolerated by the vast majority of public including childeren.
Good luck and have a pain free day!
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The greatest trick the devil ever pulled was to convince the world he never existed.
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insman
Stranger
Reged: 08/30/03
Posts: 6
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Hello,
This has also happened to me, when given iv relan while getting preped for trigger point injections. I felt like I had to get up and run.....very hard to explain, but just as you described, to the tee. I have since put, "allergic" to reglan on everything....this is a common reaction from the docs I've spoken with.
Hope this helps.
Jack
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~insman~
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flea
Enthusiast
Reged: 05/17/02
Posts: 276
Loc: Recently moved to Mid-West, bu...
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Wow, your experience with Reglan sounds quite similar to an experience I had with another anti- nausea med through an IV. I am not sure of the spelling, but from what I remember, it was called Compazine.
I had a really bad case of food poisoning this one time and it was so horrible that I thought I was going to die. Actually, from what I remember, I WANTED to die!!
I could not stop puking or, um, well how do I put it gracefully....um, I guess there is no way to put it gracefully so I will just say it...the projectile puking was free flowin' out of one end and at almost the exact moment, I was dealing with yet another form of body fluids being projected out of my poor traumatized body. It was HORRIBLE!
This had gone on for several hours even though I had not taken a sip of anything throughout the entire day. Even the thought of sipping on a small glass of 7-UP was to much to think about. So as you can imagine, I was getting quite dehydrated.
It felt like someone was wearing spiked shoes while doing jumping jacks on my stomach. By the time my husband got home from work I was in really bad shape. It freaked him out enough that he demanded I go to the ER. I realized that I was really sick so I had better listen to him.
When I got there they told me I was REALLY dehydrated so they were going to put me on an IV. Well, that sounded fine to me, heck, if they say I am that dehydrated then I probably am. The one thing I do know is I could barely move my head without getting really dizzy.
Then suddenly, without any warning (poor nurse) I threw up all over the place. It was SO nasty, it only consisted of yelloe bile considering i did not have anything else in me!
So, in order to stop the nausea and protect me from the dangerous effects of extreme dehydration the doctor said I needed to get something in me that would immediately stop the violent exit maneveurs that were taking place.
So....I got shot up full of Compazine (spelling?). It was so weird, because almost immediately I started to feel weird. Not just sick weird, but weird, weird. You know what I mean, I started to get dizzy and I could not get my body to relax. I wanted to rip that IV out of my arm. I literally began trying to do just that until my husband held my arms down.
I seriously felt like someone that needed to be committed into a psych ward. I could not remember little things and i kept asking the same questions over and over. It was nothing to laugh at because i actually thought I was going to die. I told my husband I could barely remember who I was and that was just the start of my memory loss.
Also, whenever someone spoke to me, I just stared at then with a blank stare. Their voices sounded like they were talking to me from inside a tunnel. I felt out of control as if I was going to rip that sucker out of my arm no matter what. My actions were quite bothersome to my husband since he knows I hate making a scene when I am at the doctor, and I always try to be a really easy and cooperative patient as I used to think being sweet and polite would guarantee superior car. Ya right!!
Well long story short here. I begged my husband to make them remove the IV and let me go home. They eventually did so, but they said they felt I was making a mistake. They seemed quite ilequipped to handle such a medication reaction which made me think I was the only person that had been effected from that compazine.
I also began having short term memory loss. It sounds almost too bizarre to be factual, but I swear this happened to me! I went home and crashed for several hours and when I woke up I felt much etter. But I swear, that was one of the worst experiences I had ever been through. I even think it was worse than my back surgery.
Since that experience 5 years ago, I always list compazine as the med I am allergic to. Still, to this day, I have no idea why i had such a negative reaction to the stuff, but I am not willing to try it again just to find out why i had the reaction that i did.
Now when I go to a new doctor and they ask for my allergies I list this one on top. It was not until several months ago that I was told by the nurse at my pain clinic that the reaction I had experiences was in fact an allergic reaction to the compazine through the IV, She even said there have been several people that had similar reactions.
As mean as it may sound, I really was relieved to find out others had also been through this. It somehow made me feel a lot less like a circus freak.
I am just surprised the hospital staff that had given me this stuff for the food poisoning did not recognize the bad reacxtion I was having. Not one person told me this mediocation has been known to cause problems in several other patients. Instead they sent me home believing I was the only freak of nature that this had happened to.
I was so scared when I got home. I felt as though I was having an out of body experience for several hours more.
Luckily, I think I was able to sleep it off. When I woke up from that nap my mind and thoughts were not as fuzzy as I had thought they would be.
I will never allow anyone to put compazine in my IV again. I think the dehydration was easier to handle than the tricks my mind was playing on me.
Since we both had been given anti nausea medicne that made us feel weird, maybe there is something that is in it that can mess with the persons mind.
I truly hope not, but at this point I have no doubt at all that even though the medical staff knows about possible negative reactions to these meds, they still will give them if they have them on hand. Not that they are just trying to be mean, but instead to attempt to get the patient out of the ER as soon as humanly possible.
Well, just know you are not alone. I would be interested to know if anyone else here at DB has had similar experiences.
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Flea
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Sky_Queen
Fly Girl
Reged: 12/03/02
Posts: 1962
Loc: Texas
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I agree with the poster who suggested Zofran - also Phenergan via IV is wonderful for nausea. Honestly, I've never heard of Reglan for nausea.
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MWouk
Journeyman
Reged: 08/28/03
Posts: 82
Loc: Up & Down I - 95
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I have never heard of such reactions to these meds.
Is it possible that the combination (as someone said induction of the IV or the epidural) was given too fast? I am considering epidural injections and this sounds scary! 
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MWouk
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537
Threadhead
Reged: 12/08/01
Posts: 766
Loc: west coast CA
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Well, I actually was not able to go through with the shots. I had to go home. So, I don't think it was any combo of drugs, just the Reglan. I have a "pill book" and decided to check out Reglan and it explained that some people will have a bad reaction to it, like anxiety, uncontrollable muscle movement, sweating, red blotches, diarrhea, all the things I felt. It actually kind of felt like hydro withdrawls, for me at least. I'm in the process of finding a new PM doc because I was not satisfied with how my current doc handled the situation. He treated me, not horribly, but very uncompassionately and then just walked away without offering any advice or even telling me to reshedule. I feel it's very important to be comfortable with any doctor I see and they need to show caring for their patients. He did not demonstrate that. He was kind of weird from the beginning anyway. It was almost like he was hitting on me at my consultation. But that's a different story. Anyway, I will never let anyone give me Reglan again, I would rather suffer with an upset stomach.
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Jeremiah
Agape GrandParent
Reged: 07/14/02
Posts: 705
Loc: U.S.A.
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Reglan is on my list of allergic meds. This was given me years ago after gallbladder surgery. Broke out in red welts,anxiety out the roof and felt like a doomsday feeling.Very Strange for me. So,no..I cannot and will not take this med. I have 25mg Phenergan tabs prn and they work fine.No reglan for me!YUK!
J.
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I can't see me lovin nobody but you,for all my life
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Anglwink
Veteran

Reged: 04/29/03
Posts: 605
Loc: East coast
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Flea,
I can relate yo your story very well, jowever it was a different med. Its the gas that the dentist gives to while doing dental work (I think they call it laughing gas) but I REALLY thought I was going to die, My heart was racing, and I felt like I was not in mt body, I could hear voices bt they sounded extremely far away, I was relly sacred and I can omly state that i felt the way you stated in your post. I also now take Phenergan as it is an anti-anxity med as well asclming down my stomach. Anglwink
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"Believe"
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night_shade
Threadhead
Reged: 08/26/03
Posts: 907
Loc: The State of Hockey
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Hello- I had IDENTICAL symptoms with IV Compazine (another anti-nausea med) administered in the hospital. I felt exactly the same way you describe feeling with that Reglan. It should be noted, however, that I have never had an adverse reaction to Compazine or similars (Phenergan, Vistaril, etc.) when taken orally or by IM administration.
I have no idea what happened that one time with the Compazine, but I'll never allow it to be given IV again!
Take care!
night_shade
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Never underestimate the predictability of stupidity.
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Box_of_Rain
Banned=more than one account
Reged: 09/28/03
Posts: 111
Loc: Pacific Northwest
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Old thread but I thought I'd revive it for the heck of it.
Similar reaction here. The 'anxious' reaction is not a "true" allergy but who really cares, it's not something you want to take either way. I have it written as "allergy" in my charts just to make sure some some smart arse doc doesn't try to get cute and give me anything similar. I tend to do my own homework though; sadly, the patient often does.
Actually if you have problems with Reglan, Compazine will likely do the same, and vice versa. Just a word of warning to anyone who's attention I have here.
Reglan gives me horrible dystonic reactions, looks and feels like I am possessed. I can describe it as being hell quite rightly.
This is not all that uncommon with Dopamine receptor blocking agents - including the phenothiazines (Compazine, Thorazine etc), also Hadol and especially Reglan for some reason. IMO this is bad stuff. Chemically this stuff is hideous.
Zofran is a miracle and the drug of choice for my nausea. It's ungodly expensive (thank GOD for insurance, it's about $35 per dose or something absurd like that) but well worth it; I refuse pretty much all other antiemetics.
My $.02 anyway.

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kjb595
Newbie
Reged: 10/14/03
Posts: 37
Loc: Michigan
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I can't believe my eyes! Thanks Stella for reviving this old post! I have always thought that I was crazy because I have had this SAME EXACT REACTION to compazine and also a med called Droperadol (sounds like dro-pair-a-dol)! My husband was so scared and the doctor that gave me the meds thought that I was just trying to get narcotics(he told me in the beginning of the er visit that he doesn't do narcotics for migraines!!) so he discharged me and I was up all nite long feeling like I was going to either kill someone or kill myself!
I just can't believe that i'm not the only one! It makes me feel like a much saner person knowing that!! LOL So anyways I have to add my preference to anti-nausea meds! For the past 2yrs I have gotten shots when my migraines get really bad! The meds they give me are Dilaudid 2mg and Vistoril 75mg IM and they seem to work wonderfully!! I love this med I have never once gotten an upset stomach which is pretty good considering that the dose I get is pretty hefty for a lightweight like me!! Ok I will quit rambling now!! 
Kelly
AKA: kjb595
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Box_of_Rain
Banned=more than one account
Reged: 09/28/03
Posts: 111
Loc: Pacific Northwest
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Oh yes, Droperidol is definitely included. It's another that should be contraindicated in those (like us) who have had reactions with these Dopamine receptor blocking agents. I know the names and types of meds included in this and always keep a watchful eye to make certain I am never given them again. It was terrifying, and if a doctor gives anything like that to me again after my lengthy protests written in red in my chart, I will blacken his eyes LOL
for my migraines I ususally take Zofran (stop puking) then a percocet or hydrocodone. I HATE to go in for anything so I am pushy about things I can do for myself at home. I had a vile of Nubain which I have administered IM but it kinda sucks (dislike it the way I do Stadol, ICK) so I don't keep it around anymore.
When I do go in for a shot, it's usually just at my PCP's office so it's usually limited the selection; Vistaril or Zofran mixed with Demerol, usually 100mg will suffice. Never had Dilaudid but I hear it's like being in the hands of God given IV, a little scary 
Anyway, rambling here (it's in the air) I am so glad that you got some relief from this thread, it seemed a worthy candidate for revival 
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BlackCat
Old Hand
Reged: 09/22/03
Posts: 403
Loc: Bed
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hmmm.... My cat (not the one in the picture - that's his older brother) was given Reglan last week to control / eliminate his vomiting. After two days on it, he lost his appetite and wouldn't eat or drink. I stopped it after 2 days and he continued getting weaker so I hand fed him blended cat food and droppers of pedialite water the 3rd day. He got so weak he couldn't walk without wobbling and falling that day. The next day I checked him into the hospital where he is now in a heated cage on an IV with electrolytes and getting a feeding tube inserted today.
I wonder if he had a reaction of some sort to the Reglan that I kept giving him for 2 days that made him this sick that he wouldn't eat or drink.
Anyone ever hear of reactions such as this in people who stayed on Reglan for a few days while feeling ill effects?
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537
Threadhead
Reged: 12/08/01
Posts: 766
Loc: west coast CA
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Don't know if this helps, but I was on Reglan for about 1 1/2 hours, and it took a good 24 hours to get back to normal. It was really awful. I hope your cat gets better soon.
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boyoboy
Stranger
Reged: 11/07/02
Posts: 11
Loc: USA
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This happens to me with IV Phenergan. Not pill or IM only IV. I have been told it is called a paradoxal(sp) effect. Most Dr's and hospitals know that the fix for these feelings is a shot of benadryl. It is not a true allergy but rather a reaction or side effect. I agree it is a very awful feeling. I list it as an allergy and if ever questioned I then explain.
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