Key Takeaways
- Allergies can keep your sinuses inflamed all year, leading to chronic sinusitis.
- IgE‑mediated reactions, nasal polyps, and impaired mucociliary clearance are the main bridges.
- Diagnosing the allergy link requires skin tests, blood panels, and imaging.
- First‑line treatments are antihistamines, intranasal corticosteroids, and allergen immunotherapy.
- Lifestyle changes-air filtration, nasal irrigation, and trigger avoidance-cut down flare‑ups dramatically.
Understanding Allergies and Chronic Sinusitis
Allergy‑induced chronic sinusitis is a persistent inflammation of the sinus cavities driven by allergic mechanisms. While acute sinusitis clears within weeks, the allergic form lingers, often for months or years, because the immune system never fully calms down.
The central player in most allergic reactions is ImmunoglobulinE (IgE). When you inhale an allergen-pollen, dust‑mite particles, or mould spores-IgE antibodies on mast cells recognize it, releasing histamine and other mediators that cause swelling of the nasal lining.
That swelling narrows the sinus ostia, the tiny doorways that let mucus drain. When drainage stalls, mucus builds up, creating a perfect environment for bacterial overgrowth and prolonged inflammation, which clinicians label chronic sinusitis.
How Allergic Reactions Trigger Sinus Inflammation
Three physiological steps turn a harmless allergen into sinus pain:
- Sensitisation: Your immune system produces IgE specific to the allergen.
- Late‑phase response: Hours after exposure, eosinophils flood the nasal tissue, releasing proteins that keep the lining swollen.
- Impaired mucociliary clearance: The cilia that normally sweep mucus out become sluggish, so secretions linger.
When the lining stays inflamed, nasal polyps often develop. These soft, painless growths further obstruct airflow, creating a vicious cycle.
Year‑Round Allergens: The Hidden Culprits
Most people picture spring pollen, but many allergens are present all year:
- House dust mites - thrive in bedding and carpets, releasing proteins that trigger IgE responses. \n
- Indoor mould - grow on damp walls, especially in older Manchester homes.
- Pet dander - tiny skin flakes from cats and dogs that linger on furniture.
- Cockroach allergens - common in city flats, their shed skin and droppings are highly allergenic.
If you suffer from perennial symptoms-runny nose, pressure, or headache on a rainy day-you’re likely reacting to one of these year‑round triggers.

Diagnosis: Spotting Allergy‑Driven Sinusitis
Doctors use a combination of history, tests, and imaging:
- Clinical questionnaire: Details on symptom timing, known triggers, and family history of atopy.
- Skin‑prick test (SPT): Small amounts of standard allergens are introduced into the skin; a wheal >3mm suggests sensitisation.
- Serum IgE panel: Measures specific IgE levels to common indoor allergens; values above 0.35kU/L are considered positive.
- CT scan of sinuses: Shows mucosal thickening, ostiomeatal obstruction, and the presence of polyps.
When the tests align-high IgE, positive SPT, and radiologic evidence of sinus blockage-clinicians confirm the allergy‑sinus link.
Treatment Pathways: Medications and Immunotherapy
The goal is two‑fold: calm the allergic inflammation and restore normal sinus drainage.
Therapy | Primary Action | Typical Onset | Key Side‑Effects |
---|---|---|---|
Antihistamines | Block histamine receptors, reducing sneezing and watery discharge | 30minutes-2hours | Dry mouth, mild drowsiness (first‑gen) |
Intranasal corticosteroids | Suppress local inflammation, shrink polyps, improve mucociliary function | 3-7days | Nasal irritation, occasional nosebleeds |
Allergen immunotherapy | Modifies immune response, reducing IgE over years | 6-12months for noticeable benefit | Local swelling at injection site, rare systemic reactions |
For most patients, the first step is a daily intranasal corticosteroid spray (e.g., fluticasone). If symptoms persist despite optimal spray technique, adding a second‑generation antihistamine (loratadine or cetirizine) helps control the histamine surge.
When medication alone can’t keep the inflammation at bay-especially in people with high IgE levels or multiple nasal polyps-allergen immunotherapy becomes the disease‑modifying option. Subcutaneous injections are given weekly for the first 3months, then monthly; sublingual tablets are an alternative for dust‑mite or grass pollen.
Lifestyle Hacks to Keep Sinus Passages Clear
Even the best drugs can’t beat consistent environmental control:
- Air filtration: Use HEPA filters in bedrooms; change them every 6months.
- Dust‑mite bedding: Encase mattresses and pillows in allergen‑proof covers; wash weekly at 60°C.
- Humidity control: Keep indoor humidity below 50% to discourage mould growth.
- Nasal irrigation: A daily saline rinse (250ml) clears mucus and reduces allergen load.
- Pet management: Keep cats and dogs out of the bedroom; bathe them weekly.
Combine these habits with a short‑term antihistamine before exposure (e.g., a walk in a park with high pollen) to blunt the acute spike.
When to See a Specialist: Surgery and Advanced Care
If you develop extensive nasal polyps or you’ve tried maximal medical therapy for 12weeks without relief, an ear‑nose‑throat (ENT) surgeon may recommend functional endoscopic sinus surgery (FESS). This minimally invasive procedure reopens blocked drainage pathways and removes polyps, allowing medications to work more effectively.
Post‑operative care often includes a short course of oral steroids followed by long‑term intranasal corticosteroids and, if you’re a candidate, immunotherapy to prevent regrowth.
Remember, surgery isn’t a cure for the allergy itself; it merely restores anatomy. Ongoing allergy management remains essential to keep the sinuses clear for the long haul.

Frequently Asked Questions
Can seasonal allergies cause chronic sinusitis?
Seasonal allergies can start a cycle of inflammation, but for chronic sinusitis to persist year‑round you usually need a perennial trigger-like dust mites or mould-that keeps the immune system activated continuously.
How long does it take for nasal steroids to work?
Most patients notice reduced congestion within 3‑7days, but full reduction of polyp size may require 4‑6weeks of consistent use.
Is immunotherapy safe for people with asthma?
Yes, when asthma is well‑controlled. In fact, many studies show immunotherapy improves both allergic rhinitis and asthma control, reducing the need for inhaled steroids.
What home tests can confirm a dust‑mite allergy?
A simple in‑home kit can collect dust samples for a lab‑based IgE assay. While not as definitive as a skin‑prick test, a positive result (>0.35kU/L) usually correlates with clinical symptoms.
Can I avoid surgery by using stronger meds?
In many cases, aggressive medical therapy-including a combination of high‑dose nasal steroids, short courses of oral steroids, and immunotherapy-can shrink polyps enough to skip surgery. However, if the drainage pathways remain blocked, surgery offers the most reliable long‑term relief.