Aromatase Inhibitor Basics: What They Are and Why You Might Need One

When the body makes estrogen, an enzyme called aromatase does most of the work. Aromatase inhibitors (AIs) block that enzyme so less estrogen is produced. Doctors often prescribe them for hormone‑sensitive breast cancer, but they’re also used by men on testosterone therapy and people dealing with gynecomastia.

Popular Types and How They Differ

The three most common AIs are anastrozole (Arimidex), letrozole (Femara) and exemestane (Aromasin). Anastrozole and letrozole are reversible blockers, while exemestane binds permanently. Dosages vary: anastrozole is usually 1 mg per day, letrozole 2.5 mg, and exemestane 25 mg. Your doctor will pick the one that fits your health profile.

Side Effects You Should Watch For

AIs can feel like a double‑edged sword. They lower estrogen, which helps stop tumor growth, but they also bring bone loss, joint pain, hot flashes and mood swings. Some people notice fatigue or a slight increase in cholesterol. If any symptom gets worse, call your doctor right away – sometimes a dose tweak or a supplement for bone health can help.

Before you start an AI, get a baseline blood test for calcium, vitamin D, and bone density. Many doctors suggest adding a calcium‑vitamin D combo or a bisphosphonate if you’re at risk for osteoporosis. Staying active with weight‑bearing exercise also protects your bones.

Buying AIs online can be tempting, but safety matters. Look for pharmacies that require a prescription, show a physical address, and have clear contact info. Check reviews on independent forums, not just the site’s own page. If a price looks too good to be true, it probably is – counterfeit pills won’t give you the right dose and could be dangerous.

Bottom line: aromatase inhibitors are powerful tools when used correctly. Talk openly with your healthcare provider about benefits, risks, and any other meds you take. Keep track of side effects, protect your bones, and only order from verified pharmacies. With the right plan, an AI can be a safe part of your treatment journey.