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Also, Does anyone notice a difference in effectiveness in regards to the amount of Tylenol with Hyrdocodone 10mg. (like 325mg vs 500mg)
Absolutely. 10/325s are like sugar pills for me with virtually no pain relief or "warm & fuzzies" even if I quadrupled my dosage. 10/500s, on the other hand, work very well for me but everyone's body chemistry is different.