Wish I knew enough to help. As to the idea about adrenals I'd really like to hear some follow up. Please PM or post. I may can help. This is a big interest-area of mine, as is Endocrinology in general. Since she had a stroke, I'd research the European drugs 'out there' used to treat Alzheimers. They've been pretty successful in Europe treating symptoms following stroke in the same way (same drugs) which are used for alzheimers, or dementia, whatever.
But given my interest in 'smart drugs' nootropics and all I couldn't resist responding. What are they doing in the way of examining and/or treating the electrolyte imbalance? (sodium, pottasium, etc)??
Which anti-depressant had she?
Can she learn to move around very slowly, especially after sitting for long periods? can she adapt to (temporary?) use of a walker? How about a cow-bell around her neck?
Aww boy 40something is way too young for those problems