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How much medicine do you think it would take to cause painkiller toxicity? I was just wondering because sometimes when I have alot of pain I will take up to 6 hydrocodone in one day.
This depends on quite a few factors,but the 'norm' is try not to go over 4g (4000mg) a day of tylenol(APAP). For example,if you take 6 tabs of 10/500 per day,your APAP would be 3g daily which is under the accepted toxicity level.
The other factors are whether you have a gallbladder which detoxifies meds first then sent to the liver for further breakdown. If you dont have a GB,the liver takes over this function solely.
Another factor is whether you take statin drugs(cholesterol) or drink alcohol(ETOH).Both these are known detriments for the liver and may cause abnormal liver enzymes within the organ.APAP added to the equation can cause deterioration of the liver quicker.
Hope this helps!
J.
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