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You can actually take up to 4 grams of apap a day and be alright bit I wouldn't do it on a long term basis.
In theory, but it varies from person to person and obviously, your chances of damage are a lot greater if you drink alcohol regularly.
I know people that have taken a LOT more than that for a long time and have had liver enzyme tests and all is fine.
And we have all heard the stories of people that took a lot less than that for short periods of time and died from liver failure.
I myself, am very sensative to APAP and my liver enzime levels change (indicating the early stages of damage) with even less than 4000 mg/day.
Also, if you take a lot of APAP, L-Cystine, according to several well controlled studies (although not enough for my tastes as is usually the case with herbal products; no one wants to pay for them as there is no money to be made) will help counteract much of the damaging affects on your liver.
At the very least it is an amino acid that is perfectly safe so it might be a consideration for some people (I take it at the recommendation of my doctor). www.iherb.com, amoung other places, has good prices on it.
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