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Narcotic meds can can cause menses irregularities, I haven't had a cycle since I have been 17, I'm 28 now. I asked my doc and he said that pain meds wills cause irregularites be that my problem is caused by severe endometriosis and damage from the laser surgery I had when I was 17 . So if your cycle does not return definatly go to the doc. If your not using mass amounts of narcotics you shouldn't have too much of a problem.