The snack thing is why I remembered this drug, here is one of many that I have read , I can post more descriptive ones if need, here is the first one:
http://www.crazymeds.org/desyrel.html
US Brand Names: Desyrel, Sideril, Trazalon; Trazonil
Other Brand Names: Azonz (Finland)
Beneficat (Argentina)
Bimaran (Argentina)
Deprax (Spain)
Depresil (Philippines)
Depyrel (Israel)
Desirel (Thailand)
Manegan (Argentina)
Molipaxin (United Kingdom; Ireland; South Africa)
Pragmarel (France)
Reslin (Japan)
Taxagon (Argentina)
Thombran (Germany)
Trazodil (Israel)
Trazolan (Belgium; India; Netherlands)
Trazone (Indonesia; Portugal; Taiwan)
Trittico (Austria; Colombia; Greece; Hong Kong; Italy; Peru; Switzerland)
Generic Name: trazodone
Other Forms:
Class: Antidepressant.
Read up on these sections if you haven't done so already, because they cover a lot of information about multiple medications that I'm not going to repeat on many pages. I'm just autistic that way about not repeating myself.
FDA Approved Use: Depression
Off-Label Uses: Panic/Anxiety, Sleep Disorders, Bipolar Depression, Chronic Fatigue, Fibromyalgia, Arthritis, Lupus, Irritable Bowel Syndrome, Eating Disorders
Desyrel (trazodone) pros and cons:
Pros: The antidepressant you need if you have the combination of insomnia combined with mild depression and/or anxiety.
Cons: You might just sleep a little too well.
Desyrel (trazodone) side effects:
Typical Side Effects: - headache, nausea, dry mouth, sweating, sleepiness or insomnia, and diarrhea or constipation, weight gain, loss of libido. Most everything but the weight gain and loss of libido usually goes away within a couple of weeks..
Not So Common Side Effects: Low blood pressure. General cardiac weirdness, so Desyrel shouldn't be used if you have a history or family history of heart issues, at least, not without prior clearance from a cardiologist. Since it makes you sleep better, many people report vivid or unusual dreams. Like Seroquel, another medication prescribed for insomnia alone, there's sometimes a nasty hangover the first few days after using Desyrel. It usually goes away in a day or two.
These may or may not happen to you don't, so don't be surprised one way or the other.
Freaky Rare Side Effects: Priapism so bad that surgical intervention was required to get rid of the unending hard-on. Bob Dole shouldn't have relied on Viagra to take on Bill Clinton, Bob Dole should have tried Desyrel to go mano a mano with the president. Wait, there's more. Not only can men get stuck that way, but women too, as it once caused clitoral priapism.
You aren't going to get these. I promise.
Interesting Stuff Your Doctor Probably Won't Tell You: Desyrel is best taken with food, so take it after dinner, or dessert, to ensure a quality night's rest.
Desyrel (trazodone) Dosage and How to Take Desyrel (trazodone): The initial dose is 150mg a night, taken after dinner or "a light snack." But, really, start at just 50mg if you want to wake up the next morning. If you don't respond after one week, increase it to 100mg. Unlike most other SSRIs, people respond to Desyrel rather quickly, so you can work up to that 150mg dosage after two weeks, then wait a month before increasing the dosage. After that it's an increase of 50mg a day every four days or so, dividing the dosage, until you reach the maximum of 400mg a day.
Days to Reach a Steady State: Steady state data weren't published, probably due to its having a double metabolism.
When you're fully saturated with the medication and less prone to peaks and valleys of effects. You still might have peaks of effect after taking many meds, but with a lot of the meds you'll have fewer valleys after this point. In theory anyway.
How Long Desyrel (trazodone) Takes to Work: Unlike most reuptake inhibitors, Desyrel works for 75% of people within two weeks. If it's going to work at all, that is. Give it a month, of course.
Desyrel (trazodone) Half-Life & Average Time to Clear Out of Your System: Desyrel has a double metabolism. The half-life for trazodone is 3 to 6 hours, while the half-life for its metabolite is 5 to 9 hours. Apothecon didn't publish an aggregate, so figure at least 15 hours total, or three days to clear out of your system. step down your dosage by 50-100mg.
How to Stop Taking Desyrel (trazodone): Your doctor should be recommending that you reduce your dosage by 50-100mg a day every 3-5 days if you need to stop taking it, if not more slowly than that. Based on the combined 8-15 hour half-lives. For more information, please see the page on how to safely stop taking these crazy meds.
If you've worked your way up to a particular dosage, it's usually best to spend this many days at the next lowest dosage before going down the next lowest dosage before that and so forth. This is the least sucky way to avoid problems when stopping any psychiatric medication. Presuming you have the option of slowly tapering off them.
Comments: Desyrel is the official antidepressant of Sleepy-bye Land. It is rarely prescribed as monotherapy these days. Hell, Desyrel is rarely prescribed at all, the generic trazodone is what is in all those bottles. It's mostly an add-on antidepressant in case you have insomnia combined with your depression and/or anxiety. If you respond well to SSRIs and you're not sleeping, trazodone is a good addition to your cocktail to make sure you sleep. And sleep. And sleep. If you're going for the combination of antipsychotic and antidepressant, don't mix Desyrel with Seroquel if you want to wake up any time this week. We've come across one person actually taking this combination and she has one hell of a time getting up every morning.
Manufacturers: Apothecon (original manufacturer), Pfizer (US licensee), Watson (one of several producers of the generic form)
Sample US Cost: $135 for 60 tablets of 50mg brand name Desyrel. $11 for 60 tablets of 50mg of the generic trazodone. See why the generic is prescribed a bazillion times more often than the brand?
As of 11/11/2003. Full retail for the uninsured. Go ahead and gloat, citizens of civilized countries and all of you with full medical coverage.
Sample Canadian Cost: $37 for 100 tablets of 50mg brand name Desyrel. $37 for 100 tablets of generic trazodone. You don't save much going north in this case.
As of 11/11/2003. In US dollars, for re-importation to the US. Does not include shipping charges or currency conversion charges you might incur on your credit card. Currency fluctuations will alter the price on a daily basis
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