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I'm sure you must already know this but.... Be careful with the amount of APAP you are ingesting every day by taking 6 tabs each of which contains 660(?)mg! If you are really taking that much, I would definitely switch to another similar medication with less APAP! Also, you might ask your own doc to order liver function tests on you - since APAP is so toxic to the liver. Or is the "660 mg" just a typo? Vicodin usually comes only with 500mg or 750 mg APAP in addition to the hydrocodone component...