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Whether or not there is a fee depends on your credit contract. MOST cards do not have this fee...usually the high-interest cards that are offered to people with bad or no credit will have fees for everything.
Once a customer complains to their card company IN WRITING (ALWAYS make these complaints in writing!) that they have not received, or that the merchandise was not as it was supposed to be, the card company takes over from there by contacting the vendor and basically faxing a letter that reads pretty much that unless the order details are provided and shipment verification is noted, the card will be refunding the cardholder. It is then on the merchant to provide adequate details.
I worked for an online retailer as a credit card processor (including frauds and chargebacks) and MOST of the time our company was able to provide the information that was necessary to PREVENT a chargeback. Buyer's remorse is NOT a credible reason for chargeback, but MAY qualify for "purchase protection" (many cards offer that guarantee, see your contract for details.) It IS the card issuer's right to know exactly what was purchased, by whom, when and all pertinent details of the transaction. If your card asks you what you purchased, "medication" may not be a sufficient answer. Now, they DO NOT have the right to ask you what you take the meds for...only what exactly you bought and from whom, any details you have about the vendor, etc. Just make sure to take notes during any conversation with the vendor or the card issuer.
Chargebacks do not necessarily hurt a vendor's status with Visa/MC, etc. It all depends WHY the chargeback was issued and if the vendor's positive transactions with the credit card company outweigh the negative ones.
-------------------- Never underestimate the predictability of stupidity.