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I know of several reputable OP's that have had the 'whistle blown' on them by the following two methods;
1) Disgruntled patient/employee; Go to LE and lay out everything for REVENGE. One such incident involved a very nice/caring MD that practiced in two countries. He had a patient that began to abuse. He tried to 'tenderly' divorce himself from this patient and taper him down on the drug. The patient got mad and laid a trap for the MD. If I gave the doc's name - MANY old timers would know him. He still paractices in the other country and I talk to him often. The investigation that followed ruined him professionally in this country and cost him a small fortune.
2) Sometimes patients that have been using/abusing OP's to obtain Rx's for recrrational purposes will go 'clean'. In the process of recovery, they THINK they will help others out and they THINK they are 'whistle-blowing'.... Really they are just screwing the honest people seeking treatment.
I'm sure there are other ways - but I know of a few circumstances where the above led to 'issues' for some really good/decent people.