DrugBuyers.Com: Diff. between Vintage Brand & Watson????

Yes sir, you are correct they are manufactured by Qualitest.

As for the slower onset, yet longer duration..

This is attributed to the fillers and binders each manufacture chooses to use. When you consume a tablet medication your stomach, obviously, has to break it down allowing it to enter your bloodstream. Hence, not all binders/fillers are created equal and have equal dissipation and absorption rates. An example:

Take the qualitest manufactured 10/500 (Hydro/apap) vs. the Watson 10/500.

The Qualitest "feel" more solid, smooth, unchalky. These will take a bit longer to get into your system, however the upside is the effect will last longer due to this prementioned effect. Now, on the other hand:

The Watsons - 10/500 - Blue.. These feel chalky, and even leave a noticeable residue in the container you happen to have them in. These are not as solid, the binding chemicals used to manufacture these are quite different from Qualitests labs, and these will break down and be absorbed into your bloodstream at a higher rate.

Net effect: Qualitest 10/500 (white) - Slower to dissolve - and as such slower onset. (You won't feel quite the "punch", however the overall length of pain relief would be higher, if only slightly.

Watson 10/500 (Blue) - Quicker to dissolve - and faster onset. (The "punch" or relief, will come quicker, and feel more Potent, yet it will wear off slightly quicker.)

Now, there isn't a HUGE difference in these, so I wouldn't be thinking one is superior to the others, I'm just trying to throw out a little knowledge as to why some people get various results from different manufacturers.

The same concept applies to liquid Hydrocodone (IE: your common cough syrup compounds, endal-hd, tussinex, etc) these compounds have the hydrocodone, for all practical matters, in a state of instant absorption by your blood stream (Depending on enzymes you can only absorb so much for any given time period). Thus, if you were to take the equivalent of 10mg's of Hydrocodone in the liquid form you would find that its onset of relief is MUCH faster, yet is significantly shorter in duration.

There are some cases of companies having batches of mismatched ratios of the Active ingredients in the medication. IE: perhaps a batch of 10,000 Watsons were synthetically compounded with 9.4mg's of hydrocodone instead of 10mg's. Or the other way around, they somehow got by the quality testing to have a certain batch with 11.3mg's of hydrocodone rather than the 10. This is a fairly rare occurrence, and as you can tell, logically, the small differences that can occur really would not be noticeable. (As always, there can be some batches off by a somewhat significant amount, and those ARE noticed, but that is even the more rare).

The chemistry is a fairly exact science when it comes to high quantity manufacturing, but mistakes do happen whether it be human err or not.

It is my opinion that the major difference that people notice in the brands is the types of fillers and binders they choose to use rather than a sub par amount of the active ingredient.

Sorry so long, take care =)

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-/\/eofate
"Life is 10% what happens to you, and 90% of how you react to it."