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Thanks Bronwyn! Do you use the topamax for migranes or something else? I wouldn't mind a good nights sleep or losing weight either. The nuerontin is supposed to put weight on you or at least it does for people I know that have used it but they did not use it for pain management. I'll have to make that choice. I don't use hydro all the time but just 3-4 times a year, usually for about a month or so,when I severely pull/strain my back because of my severe scoliosis. So I don't think I really need to worry too much about the liver issues but my doctor does.