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Quote:
night shade,
I am not currently taking the Stadol NS but can you elaborate on the statement you made about it & withdrawals. I heard this from someone else & am curious.
PM if you'd like. Thanks.
Stadol is an agonist/antagonist. The antagonist blocks those receptor sites and if you are opiate dependent, it can bring on withdrawal in some cases. I'll paste something that will explain a lot better than I can at the moment
Agonists: drugs that bind to and stimulate opiate receptors and are capable of producing a maximal response from the receptor.
Antagonists: drugs that bind to but do not stimulate opiate receptors and may reverse the effect of opioid agonist
Partial agonists: drugs that stimulate opiate receptors but have a ceiling effect, i.e. produce a submaximal response compared with an agonist
Agonist-antagonists: drugs that are agonists at one opiate receptor type and antagonists at another
---
Stadol contains both agonist and antagonist, so for some people it's not the best choice (for reasons stated above and why).
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