DrugBuyers.Com: Liver Damage from APAP

Well, I for one, have had liver damage, but not from hydro, or apap.... my doc put me on something called "methotrexate" which is for rheumatory arthritis, and it works, but as they slowly increased my doses, my liver becamed damaged..... and there were some symptoms, I just didn't know that they were related to each other, one of the symptoms is nausea towards the evening, I would be hungry towards dinner time, but when I started to eat, I became sick to my stomache, at the time I didn't know that it was because my liver test (SGOT) was at 186 and the ALT (SGPT) was at 69, and here is the normal range for liver function test.

Liver Test SGOT - 10 to 40 = normal range
ALT (SGPT) - 0 to 40 = normal range

Now anything higher means that your liver in inflammed, but it does take ALOT of apap to make your liver to get inflammed, cause I've taken alot of hydro in a day, and doesn't even come close to what the methotrexate did.

Honestly.... and I definatly do not recommend this.... I've taken up to 18 (5/500) hydros in a day, and that was when I herniated two discs in my back and the pain was just totally un-bearable!!! So if you multiply 500 x's 18.... OMG!!! I've never really done the math before, that means that I had taken 9000mg of apap that day!!!! And this was after my liver was inflammed the first time, and the liver test I did after that was normal so it didn't effect my liver at all, even after it had already been inflammed once, but since they have taken me off of methotrexate, but I still have to do monthly blood work ups, and since I've been off of methotrexate, my liver has not since flared up.

But you also have to realize that every person is different, as some can take high doses of methotrexate and never have a problem, I was on low doses of it when it hurt my liver, and I was not taking hydros at the time, so I knew it wasn't the apap that caused it. (I know some were thinking that )

There is also a supplement out called "milk thistle" which helps inprove liver function, I've never taken it, but many have, if you do a search, I'm sure you can read more about it, and it's available in a local health food store.

If anyone needs the normal ranges of blood work ups for liver and kidney functions, I do have them, as I request them to be mailed to me after every test. So if anyone is interested I will be happy to post them.

Thanks
Q

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Another username / alias used by "tammylynn" to bother...