tracerb
Board Addict

Reged: 03/21/03
Posts: 322
Loc: USA
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I'm just curious as to peoples' experiences with this new drug. I've been urged to take SSRI's for years by doctors and have been prescribed many, but never filled them. I recently got so badly depressed after two years of controlling my anxiety disorder with Klonopin that I finally caved in and tried this new fangled drug.
I've had alot of success with it personally. It has balanced my moods and I don't the horrible lows that I once got.
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toe
Pooh-Bah
Reged: 10/09/02
Posts: 1275
Loc: MidWest USA
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Yup. Lexapro is my 3rd SSRI. I was a prozac baby in 1989, after a couple of years went off meds and boycotted mental health in general until 1999 when I had severe major depressive episode and went on Zoloft which fixed everything very quickly all at once for about 2 months. Nearly 3 years on Zoloft decided to taper off. Started sinking, psych titrated the dose up again and I completely fell apart. Then I went on Effexor XR which nearly ruined my life (go back a few months and search for Effexor and you will find a slew of patient complaints).
I couldn't handle Effexor so I got on Lexapro. Remembering how quickly zoloft had kicked in, I had a hard time waiting for the Lex to start working. Even after all this time in treatment I want everything to work immediately . Oh wait. Maybe that's a different forum altogether.
I wanted to go on lexapro for a few reasons. One of them should be familiar to any woman who's spent years on SSRIs. Fewest incidence of sexual side effects of all of 'em. Still working on that, but I can tell that this particular issue is not exarcerbated (sp) by the drug. The other is that, of all the psych drugs, only those in the class of SSRIs have ever been statistically and throughly proven to be effective on eating disorders, bulimia in particular. And I am quite particularly bulimic.
I've been on it a few months now, at 20mg. Would like to add Welbutrin but the psych refuses. It has been reported by many people that I am "doing/looking so much better" and that I "finally have my head out of mya$$." Since adding in lamictal a month or so ago, I hve also been feeling more balanced and hopeful.
I invite anyone to pm me for lexachat!
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Procrastinate NOW.
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astrophel2
Member

Reged: 03/11/03
Posts: 152
Loc: Jo-Ja
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I'm also taking Lexapro (10mg) - anyone else find that it makes them extremely tired?!
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-Melissa
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toe
Pooh-Bah
Reged: 10/09/02
Posts: 1275
Loc: MidWest USA
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It did at first. . . not that helped me sleep at night any.
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Procrastinate NOW.
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tracerb
Board Addict

Reged: 03/21/03
Posts: 322
Loc: USA
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Yes it does make me a bit drowsy but I also take klonopin daily (have been for 2 years) to control an panic/anxiety disorder.
Lexapro has been only SSRI I have ever tried or given a fair shot and I must admit as far as I'm concerned, it's been miraculous.
Having been a depressive for most of my life but always managing to stay out of any major depressive episodes through keeping myself busy, hiking, and hard workouts, I had my first major depressive episode in 2002 after having been on klonopin for a long while. The next one came in February and I basically wound up quitting my job. I knew then I needed to do something and my doctor had recommended lexapro for me as it was reportedly helping alot of people. I took the plunge and have been faithful in taking it for over a month now. I must say the changes are dramatic, especially in my moods. I am less prone to severe mood swings (well none at all now), and my interest in things has returned. I don't get upset over stuff and the little stuff doesn't bother me as much anymore.
I do find it does make you drowsy and it's reported as one of the side effects. If it makes you drowsy I would suggest taking it at night since it's a once a day regimen with this SSRI. For me, most of the drowsiness has passed.
I can report the only side effect is decreased libido. I'm male and it definitely had sexual side effects initially (or maybe I'm just getting old lmao). They seem to be going away though.
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gabewalker
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Reged: 02/25/03
Posts: 16
Loc: pacific northwest
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I've been taking it for the last few months (10mg/day). I switched after taking Zoloft for some time, but the SA's were too much for me(loss of libido) although it worked well for me...As for the Lexapro I'm not so sure. I don't experience the loss of libido, however I am somewhat tired throughout the day, I was tired with the Zoloft as well and attributed it to depression/insomnia/interuped sleep etc....So, I plan to try something else that has more exitatiory/less sedating affect.....
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pete
Stranger
Reged: 06/06/03
Posts: 11
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Is there really a big difference between the side effects of Celexa vs Lexapro . It has been suggested by some that it is merely marketing hype by the mfg since the Celexa patent will expire very soon and the low cost generic form will be available .
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cypress434
Old Hand

Reged: 04/14/02
Posts: 422
Loc: The Deep Southern US
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My doctor said they were 'replacing' Celexa with Lexapro, and that they were exactly the same thing, so the $ thing sounds exactly right IMO.
I've tried it...didn't really notice any changes at all. I HATED Wellbutrin - it made me snap at my child for the stupidest things after 2 weeks on it, and as soon as I realized it they got flushed down the toilet.
Don't know why doctors automatically think that fibro=depression. (Fibro=getting stupid drugs that don't work worth a XXXX.)
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Cypress434
Character is what you do when no one is watching.
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toe
Pooh-Bah
Reged: 10/09/02
Posts: 1275
Loc: MidWest USA
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I have a feeling lexapro is not going to suffice when I have my next major depressive episode (projected for September). I'm on 20mg. . .
But the things is, on other SSRI's at high (in this case max) dosage, I couldn't cry. Physically. A couple of nights ago I went to see "Finding Nemo" with me girlfriend and started really bawling at one point. This was a Disney Movie, folks.
I take back what I said about the tiredness going away. Its back. Of course that might be also due to my total sloth as of late, my latest injury has kept me from running for a long time. And with no exercise comes no appetite and insomnia and with insomnia and no food comes tiredness. . .
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Procrastinate NOW.
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astrophel2
Member

Reged: 03/11/03
Posts: 152
Loc: Jo-Ja
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Toe, I know exactly what you mean about not physically being able to cry. I've always considered myself to be quite an emotionally sensitive person (who, consequently cries easily), but on Lexapro, I didn't drop a tear - not even when my s/o and I split.
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-Melissa
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toe
Pooh-Bah
Reged: 10/09/02
Posts: 1275
Loc: MidWest USA
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Quote:
Toe, I know exactly what you mean about not physically being able to cry. I've always considered myself to be quite an emotionally sensitive person (who, consequently cries easily), but on Lexapro, I didn't drop a tear - not even when my s/o and I split.
Unfortunately, Lexapro isn't even doing that for me now , while my depression is in remission. I coudn't cry on 100mg Zoloft, but can and often do on 20mg Lexapro. This has me really worried since, like I said, I am not even having a major depressive episode right now.
They need to invent a new group of anti-depressants quick, because I am scared.
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Procrastinate NOW.
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EMJ
Old Hand

Reged: 12/20/01
Posts: 471
Loc: Southeast US
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I was so glad to find a thread on this drug. My family doctor just put me on it about 2 weeks ago and it has made me so groggy I feel like a can't wake up all day. And this was just on 1/2 a pill at night. I have been going through a horrible divorce and it's really getting me down so my doctor really wants me to try the Lexapro. How long does it take for this groggy feeling to go away, I can't take something that makes me so out of it during the day even though I've been taking it at night. Any information would be appreciated. Take care all. EMJ
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I'm on the move to get past "Old Hand"
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buey
Old Hand
Reged: 01/15/03
Posts: 405
Loc: USA
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My doc put me on it to see if it would work to prevent migraines. It didn't.
To me it is like taking a sugar pill. I don't notice any difference on it or off of it.
Funny how meds effect people in different ways.
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dojo
Stranger
Reged: 09/02/03
Posts: 4
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Quote:
Is there really a big difference between the side effects of Celexa vs Lexapro . It has been suggested by some that it is merely marketing hype by the mfg since the Celexa patent will expire very soon and the low cost generic form will be available .
Celexa is basically 50% Lexapro and 50% some other molecule that has no antidepressant effect (and my cause some side effects). So the hype on Lexapro is that it's twice as potent as Celexa with fewer side effects.
I've taken Lexapro for anxiety and mild depression. It completely wiped out the depression but it seemed to have no effect on my anxiety.
The only side effects I noticed were increased drowsiness, a tendency to yawn and shiver a bit more frequently, and urinary retention (difficulty peeing).
I have a relative who's taking lexapro for depression and she loves it.
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ttrr
Journeyman
Reged: 02/27/03
Posts: 89
Loc: West Coast
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Quote:
Celexa is basically 50% Lexapro and 50% some other molecule that has no antidepressant effect (and my cause some side effects). So the hype on Lexapro is that it's twice as potent as Celexa with fewer side effects.
I've taken Lexapro for anxiety and mild depression. It completely wiped out the depression but it seemed to have no effect on my anxiety.
The only side effects I noticed were increased drowsiness, a tendency to yawn and shiver a bit more frequently, and urinary retention (difficulty peeing).
I have a relative who's taking lexapro for depression and she loves it.
That's exactly right, Dojo. Lex is a sterioisomer (1/2 basically) of the Celexa molecule. The good half. Better side-effect profile yes but no better anti-dep. efficacy really.
I have been on SSRIs for about 10 years -- Zoloft, Celexa, now Lexapro. Can't get off. The withdrawal is worse than any feeling I have ever had in my life. I want to die so I cannot get past the first week of it. I go back on. I am now on 25mg of Lex. Doc says the withdrawal could last a month if I let it go. I can't slowly go down either. I get to about 5mgs and feel terrible. I feel so helpless and just want to not have to take a little pill just to feel like I don't want to die.
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astrophel2
Member

Reged: 03/11/03
Posts: 152
Loc: Jo-Ja
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After a few months of not taking it, I'm back on lexapro! Lethargy resumes. Has anyone ever heard of a doc prescribing an antinarcoleptic in addition to lexapro?
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-Melissa
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Pocahontas
Member

Reged: 01/28/03
Posts: 124
Loc: North
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I've been on Lexapro for over six months now..40 mg q.am I don't even know that I am taking it for lack of side f/x. I do feel more "upbeat" since taking it, so i guess its working!
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~Princess Pocahontas
Aim for the moon, for if you miss you will always land amongst the stars ...
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toe
Pooh-Bah
Reged: 10/09/02
Posts: 1275
Loc: MidWest USA
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Quote:
My doc put me on it to see if it would work to prevent migraines. It didn't.
To me it is like taking a sugar pill. I don't notice any difference on it or off of it.
Funny how meds effect people in different ways.
Lexapro takes a very long time to start working. I'm taking myself as a test monitor, but I've been on enough anti-depressants to know which ones are slow and weak and which ones are fast and mind-blowing and Lexapro is lame. It took about 3 months took have even the slightest effect on me.
Update from my 6/17 post: The good old Lex never did let up on the lethargy, although that was compounded by acute and old back injuries that kept me from working out and an actual sleeping disorder. It did virtually eliminate my bulimia. What it did not do is eliminate my eating disorder or the mindset, so when a careless nurse at a disability screening let me see my weight (about 3 weeks after that last post) and I saw that I had gained at least 30 pounds in the course of Lexapro therapy alone . I actually weighed at least 50 lbs more (fully clothed) than I did last December.
So I did get myself back on Effexor. I've been on Prozac, Zoloft, and Lexapro. SSRI's, alone, aren't enough for me anymore. I got off the dreaded Lexapro. . .as I mentioned, it's simply not a strong enough drug for my severe major depressive episodes. Also, to be honest, as a PWED, I could not deal with the weight gain. I've lost over 20 lbs since I dropped the Lex. . . 28 if you want to compare my fully clothed weight to my bare nekkid wake up weight. Bear in mind I was in all senses overweight when that weight was taken in July. Bear in mind that I'm pretty honest with you guys and I'm not going to tell you that I lost all that weight just from switching anti-depressants, I am not satisfied to be back the bottom end of my healthy weight range, and would still like to weigh 50 lbs less than I did in July.
We are prescribed anti-depressants for so many reasons. I'm prescribed them because I have disabling major depressive disorder (par exemplar: I lose the ability to read) and a disgusting eating disorder. I was on the SSRI Zoloft for 3 years and it did manage to keep me from becoming completely dysfunctional until last year. SSRI's are prescribed particularly to patients with eating disorders, which is one of the reasons why the Lexapro affected my weight so drastically. I would not let my experience discourage anyone without an eating disorder from trying Lexapro, but it *is* one of the "slow and drowsy" SSRI's: like Paxil, it makes you drowsy. It takes a long time to kick in. When I started Zoloft, it was the opposite. I was manic in 2 days, sleeping a few hours a night a most (that wore of after 3-4 weeks).
My run-in with Effexor last year was tragic because I had a shrink with too much on his mind to pay any attn to my history. . . he raised my dose every week and I was 120mg of phenobarbitol froma grand mal seizure within about 6 weeks. Luckily I had rivotril and pheno of my own while he was doing this to me. Unfortunately I ran out on vacation and that's when it became apparent that this doctor had done a very very bad thing. I had to go off it, and since I can't take bupropion, react badly to TCA's, the only course of action was to try another SSRI. Well, poop on Lexapro for me. I started sloooowly back on Effexor late last summer and am on Topamax as well, so hopefully I will avoid a grand mal seizure. (They are soooo unpleasant). My Effexor needs to be upped, and the American Drug Cartel needs to invent another anti-depressant, because I'm in bad shape, but not nearly as bad as if I were still relying on SSRIs.
But it seems like some folks are having some positive effects. The effect of "pooping out" on an SSRI seems to be an effect most commonly noticed in depressive patients. The reasons Lexapro didn't work out for me are a) I am still enmeshed in my eating disorder and, in "fixing" it, I became slightly overweight, and b) I've been on SSRI's for a long time, and they are not strong enough to combat my depression.
For those who don't have that background, you have to remember that Lexapro takes a looooong time to kick in- 3 months for me. And it will not have the same effect on you that it did on me, unless you have exactly the same body chemistry, medical history, and indications for taking it. Give it a chance. There is definitely a link between serotonin availability and pain threshold.
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Procrastinate NOW.
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astrophel2
Member

Reged: 03/11/03
Posts: 152
Loc: Jo-Ja
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How is the effexor treating you?! My doctor eventually switched me to that too and slowly upped the dose to something obscene (like 225 mgs). We decided it wasn't working for me and I was in the process of tapering off when I overdosed on something else. I was in the ICU for several days, and they refused to give me anything but mucamyst. Of course, withdrawal hit me VERY HARD and it was EXTREMELY UNPLEASANT! I broke into cold sweats everytime I fell asleep, the nurses kept the thermostat on 65, I completely drenched my gown which didn't feel good against the plastic covering of the mattress. Everytime I turned my head, I got dizzy and could hear a weird scratching noise. I would even go as far as to say that I had auditory hallucinations - after I was transfered to a different unit and was able to move around, i thought I heard a TV playing. I kept hearing conga drums and the tonight show's announcer saying "Jayyyyyy Lenooooooo!" over and over again. I finally got annoyed and walked down the hall to investigate, and decided that the sounds were purely imagined. When I was FINALLY visited by the psychiatrist, he seemed surprised and alarmed that they hadn't been giving me my effexor and said "you're gonna start feeling *really* weird" - I explained that I already did and broke into tears (the nurses wouldn't listen to me). He called it "seratonin discontinuity syndrome." I got the same effect when I stopped taking celexa and lexapro, but without the cold sweats.
I'm taking nothing now, although I still have very severe social anxiety and depression. I've been on about every medication I can imagine, and nothing seems to do beans for the anxiety. I think I'm slowly realizing that nothing ever will short of intensive CBT.
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-Melissa
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astrophel2
Member

Reged: 03/11/03
Posts: 152
Loc: Jo-Ja
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BTW - in the course of my Lexapro therapy, I gained 20 pounds (and I'm not a big gal)!
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-Melissa
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Daeshay76
Enthusiast

Reged: 03/22/04
Posts: 241
Loc: TN
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I have been on Lexapro for a little over a year..i started on the 10mg and after the first few months my doc put me on the 20mg...it has helped me out alot with my panic attacks and depression...i dont even cry anymore!! i was on wellbutrin before that and it altered my moods so bad i was yelling and screaming at my beautiful children and i didnt noticed i did it until my mother recorded me doing it so i stopped taking it wellbutrin also made me feel like i just wanted to die so i hate that drug...lexapro has been my miracle i also had the sleeppy sie effects from it for about a week or so but not anymore...i wouldnt trade my lexapro for nothing else
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astrophel2
Member

Reged: 03/11/03
Posts: 152
Loc: Jo-Ja
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hmmm, maybe I should consider going back on it! Glad to hear it's working for ya! 
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-Melissa
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Daeshay76
Enthusiast

Reged: 03/22/04
Posts: 241
Loc: TN
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actaully after raeading your post about gaining weight i did too i was at 118 and i am now at 125 not sure if its from themed or not but i am glad i did put some weight on
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L3PA
Journeyman
Reged: 12/16/01
Posts: 59
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I was put on Effexor XR last month with Methadone. My doc says that the Effexor "potentiates" the methadone. Perhaps, but it surely does something!
L3Pee(a}
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astrophel2
Member

Reged: 03/11/03
Posts: 152
Loc: Jo-Ja
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Effexor - now that is an entirely different post! Effexor withdrawal is EXTREMELY uncomfortable. I was on 225 mg and because I was hospitalized, they didn't give me my meds. I'm talking about auditory hallucinations, sweating so bad that my gown and sheets were completely soaked in a 65 degree room, "hearing" my eyes move... somehow, and nauseating dizziness. I will NEVER use that drug again!!
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-Melissa
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yawkaw3
Pooh-Bah

Reged: 03/22/03
Posts: 1172
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The only thing I ever got out of any SSRI was just being distanced from emotion. I could perceive I was happy or sad, and anything in between, but it didn't feel like that. On Zoloft I had significant sexual side effects as well.
I'm happy for anyone they work on, but they just didn't do it for me. In my case, opioids (except for Suboxone- buprenorphine has been shown to be an effective antidepressant, do a Medline search) caused my depression symptoms- I had no history of it before getting on them. I tried a lot of stuff, med and non-med, and it took years before I found a good therapist, but when I did it made all the difference- I realize that's not for everybody, but it was what worked for me.
-yawkaw
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holden99
Newbie

Reged: 03/23/02
Posts: 39
Loc: Michigan
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I have been on effexor for depression also. That medication really messed me up. Immediately after the first couple of days I started experiencing almost every side effect listed. I was miserable but I was expecting to experience some rough going until my body adjusted to the med. After about 3-4 weeks the med was finally adjusted in my body and the side effects went away but it was a very rough 3-4 weeks. After being on it about 6 months I ran out of the med and didn't take it for about 4-5 weeks until I could afford to buy more and by that time my body and readjusted to not having it and so when I started taking it again I started going through all the side effects and readjustments again. I wasn't up to going through that again and decided to stop taking and I WILL NEVER go on that med ever again...I call the DEMON medication. I just couldn't hack it.
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Anthgonz41
Newbie
Reged: 07/15/04
Posts: 45
Loc: New Jersey, USA
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10mg lexapro made me jumpy, slightly stimulated, achy, insomnia and generally felt like a mild opioid withdrawal. I guess its just my body chemistry, since everyone reacts differently to different medications but I felt I should put it out there for those who may suffer the same adverse effects...your not alone.
The next day I felt a general mood lift (placebo?) and had a little more energy then normally.
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barett
Stranger

Reged: 07/07/04
Posts: 7
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My wife put on 30 lbs. with Lexapro, and she was pretty heavy to begin with. She was not happy and quit taking it.
Barett
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scrufffles
Newbie
Reged: 03/13/04
Posts: 44
Loc: Hocking Hills, OH
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I came off of celexa over a year ago. I know people who stopped taking it and no more probs than a bit of dizziness, but I went through much more. I'm glad for those who don't suffer but for those who do, I went through it, too.
When I took it, it worked great, almost too great. I am a very over emotional and sensitive person. But on celexa I could sit right through a heated, insulting argument and feel no anger, and almost start laughing. I felt very distanced and untouchable. This was wonderful for a while because all I did was cry before starting on it. But I stopped taking it because I stopped being able to cry, period. I thought it was time for me to deal with things in my life with emotion. I am not putting those down who still take it, if it helps you, I understand. I'm just saying this being it was a life changing experience for me.
I tried to stop cold turkey, dumb idea!!!
I, too, heard things while I was trying to sleep and I'd yell at my husband to turn off the TV only to find him right in bed next to me and the TV off. My jaw hurt like electric shocks were running through it. (That is a side effect shared by many during w/d from this, you can look up info). I was always dizzy, sick, tired, and didn't want to eat. I went from being 165, a bit pudgy for me, to being 125 in a month and a half. I literally would lay in bed for 23 hours a day, having no energy to eat or do anything normal. I didn't shower either, it was yucky. My room turned from being a clean sanctuary to a trash dump. Also, if I turned my head left or right too quickly, the whole room in my vision range became a trail like comet. What I saw while turning my head became a slow moving comet that slowly settled into my new field of vision. That was very strange. I was on no other meds at the time. That was the worst withdrawal I have ever encountered in my life. Please taper off if you decide to stop taking it, don't do what I did! It took me 6 months afterwards to clean myself, my mind, and my house and life up after that. The withdrawal "syndrome" should be more fully explained and explored to help those when it's time to go through it. Like I said, not everyone has this problem, but it's best to taper just in case.
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