DrugBuyers.Com: Vardenafil

Vardenafil - Levitra

LEVITRA® is an oral therapy for the treatment of erectile dysfunction. This monohydrochloride salt of vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).

Vardenafil HCl is designated chemically as piperazine, 1-[[3-(1,4-dihydro-5- methyl-4-oxo-7-propylimidazo [5,1-f] [1,2,4] triazin-2-yl)-4- ethoxyphenyl]sulfonyl]-4-ethyl-, monohydrochloride

Vardenafil HCl is a nearly colorless, solid substance with a molecular weight of 579.1 g/mol and a solubility of 0.11 mg/mL in water. LEVITRA is formulated as orange, round, film-coated tablets with "BAYER" cross debossed on one side and "2.5", "5", "10", and "20" on the other side corresponding to 2.5 mg, 5 mg, 10 mg, and 20 mg of vardenafil, respectively. In addition to the active ingredient, vardenafil HCl, each tablet contains microcrystalline cellulose, crospovidone, colloidal silicon dioxide, magnesium stearate, hypromellose, polyethylene glycol, titanium dioxide, yellow ferric oxide, and red ferric oxide.

LEVITRA is indicated for the treatment of erectile dysfunction.

LEVITRA@ (Luh-VEE-Trah) (vardenafil HCL) Tablets

Read the Patient Information about LEVITRA before you start taking it and again each time you get a refill. There may be new information. You may also find it helpful to share this information with your partner. This leaflet does not take the place of talking with your doctor. You and your doctor should talk about LEVITRA when you start taking it and at regular checkups. If you do not understand the information, or have questions, talk with your doctor or pharmacist.

What important information should you know about LEVITRA?

LEVITRA can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. A sudden drop in your blood pressure could cause you to become dizzy, faint, or have a heart attack or stroke.

Do not take LEVITRA if you:

take any medicines called "nitrates."

use recreational drugs called "poppers" like amyl nitrate and butyl nitrate.
take medicines called alpha blockers.

(See "Who Should Not Take LEVITRA")

Tell all your healthcare providers that you take LEVITRA. If you need emergency

medical care for a heart problem, it will be important For your health care provider to

know when you last took LEVITRA.

What is LEVITRA?

LEVITRA is a prescription medicine taken by mouth for the treatment of erectile dysfunction (ED) in men.

ED is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. A man who has trouble getting or keeping an erection should see his doctor for help if the condition bothers him. LEVITRA may help a man with ED get and keep an erection when he is sexually excited.

LEVITRA does not:

cure ED

increase a mans sexual desire

protect a man or his partner from sexually transmitted diseases, including HIV. Speak to your doctor about ways to guard against sexually transmitted diseases.

serve as a male form of birth control

LEVlTRA is only for men with ED. LEVlTRA is not for women or children. LEVITRA must be used only under a doctors care.

How does LEVITRA work?

When a man is sexually stimulated, his bodys normal physical response is to increase blood flow to his penis. This results in an erection. LEVITRA helps increase blood flow to the penis and may help men with ED get and keep an erection satisfactory for sexual activity. Once a man has completed sexual activity, blood flow to his penis decreases, and his erection goes away.

Who can take LEVITRA?

Talk to your doctor to decide if LEVITRA is right for you.

LEVITRA has been shown to be effective in men over the age of 18 years who have erectile dysfunction, including men with diabetes or who have undergone prostatectomy.

Who should not take LEVITRA?

Do not take LEVITRA if you:

take any medicines called "nitrates" (See "What is the most important information I should know about LEVITRA?). Nitrates are commonly used to treat angina. Angina is a symptom of heart disease and can cause pain in your chest, jaw, or down your arm.

Medicines called nitrates include nitroglycerin that is found in tablets, sprays, ointments, pastes, or parches. Nitrates can also be found in other medicines such as isosorbide dinitrate or isosorbide mononitrate. Some recreational drugs called "poppers" also contain nitrates, such as amyl nitrate and butyl nitrate. Do not use LEVITRA if you are using these drugs. Ask your doctor or pharmacist if you are not sure if any of your medicines are nitrates,

take medicines called "alpha blockers." Alpha blockers are sometimes prescribed for prostate problems or high blood pressure. If LEVlTRA is taken with alpha blockers, your blood pressure could suddenly drop to an unsafe level. You could get dizzy and faint.

you have been told by your healthcare provider to not have sexual activity because of health problems. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.

are allergic to LEVITRA or any of its ingredients. The active ingredient in LEVITRA is called vardenafil. See the end of this leaflet for a complete list of ingredients.

What should you discuss with your doctor before taking LEVITRA?

Before taking LEVITRA, tell your doctor about all your medical problems, including if you:

have heart problems such as angina, hem failure, irregular heartbeats, or have

had a heart attack. Ask your doctor if it is safe for you to have sexual activity.

have low blood pressure or have high blood pressure that is not controlled

have had a stroke,

or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome)

have liver problems

have kidney problems and require dialysis

have retinitis pigmentosa, a rare genetic (runs in families) eye disease

have stomach ulcers

have a bleeding problem

have a deformed penis shape or Peyronies disease

have had an erection that lasted more than 4 hours

have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia

Can other medications affect LEVITRA?

Tell your doctor about all the medicines you take including prescription and non- prescription medicines, vitamins, and herbal supplements. LEVlTRA and other medicines may affect each other. Always check with your doctor before starting or stopping any medicines. Especially tell your doctor if you take any of the following: medicines called nitrates (See "What is the most important information I should know about LEVITRA.")

medicines called alpha blockers. These include Hytrin® ( terazosin), Flomax® (tamsulosin), Cardura® (doxazosin), Minipress® (prazosin) or Uroxatral® (alfuzosin).

medicines that treat abnormal heartbeat. These include quinidine, procainamide, amiodarone and sotalol

ritonavir® (Norvir) or indinavir® (Crixivan)

ketoconazole or itraconazole (such as Nizoral® or Sporanox®)

erythromycin

other medicines or treatments for ED

How should you take LEVITRA?

Take LEVITRA exactly as your doctor prescribes. LEVlTRA comes in different doses (2.5 mg, 5 mg, 10 mg, and 20 mg). For most men, the recommended starting dose is 10 mg. Take LEVITRA no more than once a day. Doses should be taken at least 24 hours apart. Some men can only take a low dose of LEVITRA because of medical conditions or medicines they take. Your doctor will prescribe the dose that is right for you.

If you are older than 65 or have liver problems, your doctor may start you on a lower dose of LEVITRA.

If you are taking certain other medicines your doctor may prescribe a lower starting dose and limit you to one dose of LEVlTRA in a 72-hour (3 days) period.

Take 1 LEVITRA tablet about 1 hour (60 minutes) before sexual activity. Some form of sexual stimulation is needed for an erection to happen with LEVITRA. LEVITRA may be taken with or without meals.

Do not change your dose of LEVITRA without talking to your doctor. Your doctor may lower your dose or raise your dose, depending on how your body reacts to LEVITRA. If you take too much LEVITRA, call your doctor or emergency room right away.

What are the possible side effects of LEVITRA?

The most common side effects with LEVITRA are headache, flushing, stuffy or runny nose, indigestion, u p s e t stomach, or dizziness. These side effects usually go away after a few hours. Call your doctor if you get a side effect that bothers you or one that will not go away.

LEVITRA may uncommonly cause:

an erection that won't go away (priapism). If you get an erection that lasts more than 4 hours, get medical help right away. Priapism must be treated as soon as possible or lasting damage can happen to your penis including the inability to have erections .

vision changes, such as seeing a blue tinge to objects or having difficulty telling the difference between the colors blue and green.

These are not all the side effects of LEVITRA For more information, ask your doctor or pharmacist.

How should LEVITRA be stored?

Store LEVITRA at room temperature between 59" and 86" F (15' to 30" C).

Keep LEVITRA and all medicines out of the reach of children.

General Information about LEVITRA.

Medicines are sometimes prescribed for conditions other than those described in patient information leaflets. Do not use LEVITRA for a condition for which it was not prescribed.

Do not give LEVITRA to other people, even if they have the same symptoms that you have. It may harm them.

This leaflet summarizes the most important information about LEVTTRA. If you would

like more information, talk with your healthcare provider. You can ask your doctor or pharmacist for information about LEVITRA that is Written for health professionals.

For more information you can also visit www.LEVITRA.com, or call 1 -866-LEVITRA.

What are the ingredients of LEVITRA?

Active Ingredient: vardenafil hydrochloride

Inactive Ingredients: microcrystalline cellulose, crospovidone, colloidal silicon dioxide,

magnesium stearate, hypromellose, polyethylene glycol, titanium dioxide, yellow ferric oxide, and red Ferric oxide.

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