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gboronc
Newbie
Reged: 01/27/03
Posts: 49
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I usually get the watson 10/325. they are alright. Everyone says mallies are weak. I have not had the mallie 10/325 but i do get the mallie 5/325 monthly from my local doc. and i personnaly think mg for mg the mallies work much better for me than the watson. less bad effects.
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boylston
Newbie
Reged: 07/23/02
Posts: 32
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Quote:
First i said "akin". In that situation common sense would tell you that they won't sue themselves, but, maybe you should ask yourself what their reason would be for developing another EXACT replica of a med that they produce with the only difference being labeling. I was told by a chemist and a compounding pharm that drug companies hold an exclusive patent on a med for a period of time and then other companies will make "generic" versions of the med changing common ingredients so not to duplicate the original med and act against the original patent.
1) Why would Watson manufacture both brand-name Norco and a generic replica? Elementary. (Sorry, couldn't resist. ) There's a market for brand-name Norco, despite the higher price, and Watson would be foolish not to meet this demand, especially given the profit margin.
Yet, most patients are going to buy generics. Why? First, most docs seem to write scripts "may substitute," and the pharmacy will fill such scripts with a generic if possible. (In some states, they are legally required to do so, probably to discourage resale of the drugs on the street. It's much easier for a dealer to sell a pill stamped "VICODIN" than one with a cryptic alphanumeric code.) Second, most insurance plans provide a financial incentive for patients to use generics. Third, many folks want to buy their meds as inexpensively as possible.
The market for generic Norco is big. In fact, it's bigger than the market for the brand-name product. So naturally, Watson wants a piece of the action.
Watson gets to have it both ways. They can be the exclusive manufacturer of brand-name Norco, because that name is their registered trademark. And they also get to make money by meeting some of the demand for the generic equivalent.
Of course, as another poster pointed out, Watson isn't going to volunteer that their generic is identical to their brand-name Norco. They'll gladly sell brand-name Norco to those willing to pay for just that: a brand name.
2) Your chemist and compounding pharmacy seem to have a fundamental misunderstanding of how generic drugs become available. It's not a matter of changing the binder and other inactive ingredients to get around a patent--that won't work. Rather, generics become available when the brand-name's patent expires.
Let's take Cialis as an example. Can Acme Pharmaceuticals make a generic equivalent by using a different binder and other inactive ingredients with tadalafil? No--that's still patent infringement. Rather, Acme will wait until the patent on Cialis expires, at which point they can make their own generic tadalafil tablets.
3) I'm sure that for some folks, different binders and other differences between generics and brand-name drugs may make a meaningful difference. I still submit, though, that for the majority of folks, it's all in their heads. Consider: how come we never see posts saying something like, "Barr's generic diazepam works better for me than Roche's brand-name Valium"? Whenever a preference is expressed, it's always for the brand-name product.
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potatoboy99
Permanent Fixture

Reged: 02/04/03
Posts: 1297
Loc: Deep North (East)
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Quote:
hey, thanks for that timely response... ...are they (Mallinckrodt M367 ) the same potency as the watson 853 or worse or better?...any thoughts on that?
I long ago joined the crowd that reports the Mallies causing unpleasant side effects and reduced effectiveness, when compared to either Norco or other generics.
Mallies give me gas, and they leave a funny lingering taste in my mouth. Etc, etc etc. Lots of people have similar reactions.
However, I have never noticed any difference at all between Norcos and Watsons. The Watsons may very well contain lower quality 'gradients" or binders or whatever, but my feeling is that they are a virtually identical product
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Laurelolo23
Stranger
Reged: 02/24/04
Posts: 15
Loc: D.C.
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Howdy. A Vicodin ES had 750 mg of APAP in it; if your system is that sensitive, than you are reactive to the adjunct medications, i.e. the acetaminophen. You feel better because the APAP really does help the hydro do its job. As far as I can tell--no dice for me.
That is my rationale for having my meds compounded, so I get the lowest dose of APAP allowed by law (160 mg), but other than that, if its yellow and a 10/325--I can't tell the difference. I never have--I always buy generics, because I just can't tell!
But I do agree with the lab work, as a college student, I crushed up a Percocet and a generic Perc, ran them through a high-pressure liquid chromatograph, and saw the differences that my body couldn't feel.
I do like to pre-medicate with 400 mg of Tagamet (cimetidine, and yes, the store brand WILL work)and NAC (n-acetyl cyteine) about 45 minutes before the hydro--the Tagamet prevents the hydro from being metabolised so quickly and the NAC helps to "mop up" all the poisonous APAP metabolites that could otherwise harm your liver. Otherwise, I wish my system was that sensitive to meds, I could eat a handful of Darvon and nada...
Cheers,
Lolo
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The last time somebody said, "I find I can write much better with a word processor," I replied, "They used to say the same thing about drugs."-Roy Blount Jr.
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tklynch2
Stranger
Reged: 10/31/02
Posts: 14
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Has anyone on here ever heard of the Orange Book for generic drugs? I went to a Costco in NJ about 7 years ago
with a Lortab 7.5 prescription and asked that they fill it generically. When I got it filled in NY it was automatically filled generically unless the Dr. specified DAW. Anyway, the pharmacist told me that it may not be available as a generic in NJ, because NJ was the strictest state in the nation when it comes to what constitutes a true generic. He said he would have to check the Orange Book. It was in there and I got it, but it has always bothered me that there would be a need for such a book in the first place and that there are generic drugs that do not work the same as their name brand counterparts.
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Pocahontas
Enthusiast

Reged: 01/28/03
Posts: 286
Loc: North
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Quote:
Has anyone on here ever heard of the Orange Book for generic drugs?
Actually, I think I just downloaded that book from the internet this week! Is it the orange book by the DEA? I know it is a PDF file and part of the name was "orange book 2004"....i'll have to go look at it! I just dl'd it, didn't read it yet.....
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~Princess Pocahontas
Aim for the moon, for if you miss you will always land among the stars .. ***
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jsa9
Stranger
Reged: 07/29/02
Posts: 9
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Hi friends, i need an expert, well sort of. Just a simple question, which one of the three would you go with. Ocean pills looks like history. Yougotmeds.com---Medsmadesimple.com---or Pacificblue.com? I know ill get different positions, but i need to hear what you good friends have to say, thanks,, jsa9
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