libbo
Stranger
Reged: 06/30/04
Posts: 17
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I have been taking hydro for about the past year for my back (several injuries and extra vertabrae in my lumbar area). I have only upped my dose one time about 5 mos. ago. Now, all of a sudden, everytime I take it, I get extremely nauseous. This has never happened before as I have a strong stomach. And don't tell me to take it with food because I always do and always have. My dr. gave me Prevacid thinking it was something called gastritis but that hasn't helped. I was just wondering if my body is rebelling against me for taking all the acetaminophen. Does anyone have any thoughts or ideas about why this is happening? I don't know which is worse now, the pain or the nauseau. Thanks alot to anyone with advice.
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effie1
Newbie
Reged: 11/03/04
Posts: 38
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good question although it does the same to me! I think it makes many nauseous so it is not uncommon at all. Many require phenergan or compazine when they take it to prevent the nausea.
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libbo
Stranger
Reged: 06/30/04
Posts: 17
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Yes, I know it makes alot of people sick but it has NEVER made me sick until about 2 weeks ago. That is the strange part.
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corbe
Newbie
Reged: 07/15/04
Posts: 28
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It only makes me sick when my Body is telling me, WHOA dude, thats 60mg today, and of course I only return to the toilet Good Beer the wrong way. Oh, such is Life. Due to finacial circumstances I'm on 12 wal-Mart Ibuprophens a day and still hurting. I could go to my Dr. but I don't have a gun (I'm, kidding, of course), but he's a cut happy MoFo. After 5 incinsions I've realized that, yes,  I took the Short Bus to School, whaabouit?
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IMSUSCOT1
Threadhead
Reged: 10/23/02
Posts: 892
Loc: usa
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You don't mention what your total daily dose is & of which hydro/apap combo BUT the maximum daily allowable dose for tylenol(acetominophen) is 4 grams or 4000 mg...and most docs take that into consideration when calculating your dosage...if your concerned about whether your getting to much tylenol you can caluculate & if necessary request a different combo from your doc...you can also request the draw your blood & check your liver enzymes and that will rule out problems with your liver which is what Tylenol would affect...you don't give your age but if your near 40, fair & female they could also check your gall bladder...there's a lab they can draw to check that too...as sometimes gall stones will show up in this patient population and complaints of nausea after eating is a specific symptom for this disorder...then if all that checks out, while your at your doc why not ask for phenergan or compazine....you can get suppositories if your comfortable with them or get tablets & take them about an hour BEFORE your dose of hydro...you should develop a tolerance within 2 weeks of consistent dosing at the higher strength and this side effect should go away....there are other signs of liver damage that will show up usually before symptoms such as GI distress so if your urine is a normal color, I really doubt APAP and your liver is your problem, BUT your doctor should hear about this to decide if it's just a delayed side effect to an increased blood level after consistent dosing at the higher dose...sometimes it takes awhile for these things to catch up....
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looseliz
Journeyman
Reged: 11/09/04
Posts: 64
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anything over 325mg. of acet. makes me very nauseas. I learned that from presto meds when they sent me 10/750 or 10/500's, I can't remember except it was not what I ordered so the acet. may be too much for you. Try a lower dose.
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poppyale
Member
Reged: 06/15/04
Posts: 140
Loc: united states of america
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Hey libbo,have you also felt very tired and just give out feeling.Do you just feel like laying in bed and not moving?
if so PM me the same thing happened to me about 5 or6 months ago!!
LATER
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rara
Member
Reged: 11/16/02
Posts: 133
Loc: Oz
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IMSUSCOT1 you are right on with that. Ive even been reading that a lot of liver specialists are of the mind that 4000mg per day is still way too much & over time will cause damage. It's not common but children taking those acetominophen (we call it paracetemol) syrups for kids in the prescribed doses can sometimes suffer severe liver damage as a result.
Luckily for us all the liver is the only organ that regenerates itself as long as there's no cirrhosis & that depends on catching whatever is inflaming your liver before that kind of damage sets in.
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deborah7
Journeyman
Reged: 04/16/04
Posts: 71
Loc: Northeast USA
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Quote:
anything over 325mg. of acet. makes me very nauseas. I learned that from presto meds when they sent me 10/750 or 10/500's, I can't remember except it was not what I ordered so the acet. may be too much for you. Try a lower dose.
Thank you looseliz. That is exactly what happens to me...the higher the acet. level, the more nauseous I feel. I have told my doctor on more than one occasion I believe the acet. is making me sick to my stomach. He just suggested taking it on a full stomach. I told him I had been doing that. He kind of shrugged and told me to take an antacid.
Have a good night.
Deb
--------------------
Though the mills of God grind slowly,
yet they grind exceeding small;
Though with patience He stands waiting,
with exactness grinds He all.
Henry Wadsworth Longfellow
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jack_in_ca
Journeyman
Reged: 06/01/03
Posts: 50
Loc: California
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Quote:
I have been taking hydro for about the past year for my back (several injuries and extra vertabrae in my lumbar area). I have only upped my dose one time about 5 mos. ago. Now, all of a sudden, everytime I take it, I get extremely nauseous. This has never happened before as I have a strong stomach. And don't tell me to take it with food because I always do and always have. My dr. gave me Prevacid thinking it was something called gastritis but that hasn't helped. I was just wondering if my body is rebelling against me for taking all the acetaminophen. Does anyone have any thoughts or ideas about why this is happening? I don't know which is worse now, the pain or the nauseau. Thanks alot to anyone with advice.
With me, it comes and goes. Usually I have no problems, but sometimes I'll take just one 5/500 Vicodin and get nauseated. Can't figure it out, it's unpredictable, can happen whether or not I've eaten, usually I don't eat before taking hydro and do fine. Weird.
Peace,
Jack
--------------------
"Hello, Saddam?...George...Yeah, I know...my bad..."
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sam001
Journeyman
Reged: 02/03/04
Posts: 72
Loc: Nordstroms
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Quote:
I have been taking hydro for about the past year for my back (several injuries and extra vertabrae in my lumbar area). I have only upped my dose one time about 5 mos. ago. Now, all of a sudden, everytime I take it, I get extremely nauseous. This has never happened before as I have a strong stomach. And don't tell me to take it with food because I always do and always have. My dr. gave me Prevacid thinking it was something called gastritis but that hasn't helped. I was just wondering if my body is rebelling against me for taking all the acetaminophen. Does anyone have any thoughts or ideas about why this is happening? I don't know which is worse now, the pain or the nauseau. Thanks alot to anyone with advice.
Libbo,
Just wondering if you've switched brands of hydro recently? Maybe the different fillers in generics are contributing to your gastric issues.
Hope you get to feeling better, I agree with you that nausea can be just as uncomfortable as pain.
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lincoona
Journeyman
Reged: 11/24/04
Posts: 74
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Seems to me if you take a Tagamet before or with your Hydro you sould be better off in more ways than one, according to the "drug interaction" section of drugs.com:
"You have searched for drug interactions between the following drugs: Tagamet HB,Lortab
Please note: only generic drug names are displayed.
cimetidine and acetaminophen-hydrocodone (moderate Drug-Drug)
Description:
MONITOR:
Cimetidine may increase the action of narcotic analgesics. Cases of respiratory depression and apnea have been reported. The mechanism is unknown.
MANAGEMENT:
Patients' vital signs should be closely monitored while receiving this combination. If clinically significant respiratory depression occurs, the drugs should be withdrawn. The use of a narcotic antagonist, such as naloxone, may be needed.
Animal studies and some limited human studies have suggested that cimetidine may decrease the potential hepatotoxic effects of acetaminophen. The mechanism may be related to reductions in the rate at which reactive intermediate metabolites are formed. Not all studies have confirmed the occurrence of this interaction. No alterations in dosage are necessary."
Sounds too good to be true, except for that "respiratory depression" thing...
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tone
Veteran
Reged: 06/29/03
Posts: 554
Loc: Chicago
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i dont believe it has anything to do with your stomach directly. its the drugs effect on the nervious system that causes nausea. one of the possible effects of opioid receptors being stimulated is nausea, so its not your stomach, its the nervious systems control over it. so the solution could be another nervious system drug. antihistamines are one, dramamine, diphenhydramine. youd probably want to take as little as possible, maybe even a 3rd of a diphenhydramine (benedryl, generics) would reduce nausea
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woolius
Member
Reged: 02/08/02
Posts: 163
Loc: US
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I also experience nausea when I take hydro 7.5/750 so I try to take with food and phenergan. Seems to help most of the time.
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juliah1
Journeyman
Reged: 11/08/04
Posts: 50
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I like the tagament/hydro combo. Works well any way you look at it
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yawkaw3
Pooh-Bah
Reged: 03/22/03
Posts: 1193
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Listen to IMSU on this.
If you're taking the same dose for a while and out-of-the-blue, you're suddenly getting nausea, it's time to have a liver profile done. Simple blood test at any doctor's office.
If you are getting an unexplained rash, then you've got some bigger problems- that is a very early sign of liver damage.
There is hope if this is happening to you because the liver can regenerate approximately 3/4 of itself. But you need to get to a doctor.
Sudden nausea is not normal. It's not something that naturally happens long-term with opioid use if you're tolerant and haven't changed your dose. It has everything to do with APAP. Masking this with anti-nausea meds and antacids is doing yourself a disservice *IF* it's related to the APAP.
-yawkaw
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tone
Veteran
Reged: 06/29/03
Posts: 554
Loc: Chicago
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Quote:
Sudden nausea is not normal. It's not something that naturally happens long-term with opioid use if you're tolerant and haven't changed your dose. It has everything to do with APAP.
-yawkaw
So right, Please ignore my last post because while opioids themselves cause nausea, it is NOT normal for it to just suddenly happen if on the same dose. i am sorry, listen to yawkaw on this one. thats like the dumbest post i ever made, i totally forgot about your problem being sudden while on the same dose when i was writing it. i am so sorry
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yawkaw3
Pooh-Bah
Reged: 03/22/03
Posts: 1193
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You're way too hard on yourself tone. I am trying to catch up and I see you've had some well-written posts lately. You've been a big asset to this forum.
-yawkaw
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PugDog78
Newbie
Reged: 10/26/04
Posts: 34
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I take hydro and I tend to get an itchy rash right under my arm pits.Sometimes on my forehead.
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yawkaw3
Pooh-Bah
Reged: 03/22/03
Posts: 1193
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Well that could just be from sweating caused by opioids.
If you're not taking large doses of APAP, a dermatologist can deal with that pretty easily. If you are, it's what I talked about.
You're weclome to PM me if you like and discuss thsi in more detail.
-yawkaw
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