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Has anyone tried combining different benxodiazepines are staggering doses to achieve a desired effect?
For instance, I like the effects of Ativan for my flight anxiety. But after the flight, I can feel kind of a tired, let down feeling usually with a mild headache as the Ativan wears off. I take a 2mg does an hour before flying.
Might it be better if I took maybe .25mg or .5mg of Rivotril/Klonopin and 1mg of Ativan instead of 2mh Ativan so that I get some of the clinical effect characteristics I like from the Ativan but the Klonopin lasts longer so the accumulative effect of the two benzos will be a similar peak effect but with a longer tapering offset? Has anyone tried something like this?
The other option I was thinking would be to maybe take 1.5mg of Ativan an hour before the flight and then another .5mg of Ativan about an hour or two later. I think the peak effect of Ativan is at about two hours, so if I took another .5mg 1-2 hours later, it could keep the plateau longer and effectively make the offset more gradual do to the staggering of the doses.
It seems most people take these drugs 3 times a day, with the third right before bed so they never feel the effect of the drug wearing off since they are asleep. Since I only take one dose for air flight, I end up have to feel the offset in the middle of the day sometimes while at work. I want to minimize the amount of drugs I take for my flight anxiety (while still getting a significant enough effect to help me) but make the offset of the drug be barely noticeable.
Some might say just go with Klonopin/Rivotril by I prefer the anti-anxiety, muscle-relaxing characteristics of the Ativan. The valium makes me fee a little too groggy and has a huge half life so it stays in your system (although not very noticeable) for several days.
What are other's thoughts/experience on combining or staggering dosages?
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Stardog Member
Reged: 08/28/04
Posts: 195
Loc: Where it all Begins
I've combined benzos and just ended up feeling numb. They have different half-lives, binding affinities, and bodily distribution, but in the end, they work on the same receptors. Anyway, that's my experience.