Pickledoo
Old Hand
Reged: 09/20/02
Posts: 409
Loc: New England
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Hey there folks!
Any thoughts on the similarities, differences, comparisons?
Thank you in advance for your opinions and facts.
Much regard,
Pickledoo
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night_shade
Threadhead
Reged: 08/26/03
Posts: 907
Loc: The State of Hockey
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Having used both separately and concurrently (and presently using oxy for break through pain,) I will contribute my personal experience...
It took comparatively high doses of morphine (specifically MSContin at a range of 100-160mgs every 8 hours) to give me adequate pain relief. I also had more of the physical side effects with morphine than I did/do with oxycodone (especially nausea, constipation, sweating and pinpoint pupils.) It was however, by itself and in conjunction with oxycodone, a very effective pain management tool at appropriate doses.
Morphine administered IV drip/PCA pump, however, was an absolutely ABYSMAL pain control mechanism for my post-op pain. I do not know what the dose was, but it was so ineffective that I made the staff remove my IV and requested oral medication instead. This is no exaggeration. I got ZERO pain relief from the slow drip--even though I got great relief from the sustained-release oral formulary of the same drug. A paradox, perhaps?
As far as oxycodone, it has always been a great pain reliever for me. The biggest problem I have with oxy is rapid tolerance development. After continuous administration for a few weeks, the medication loses its effectiveness substantially.
Those are my abbreviated experiences with those two drugs.
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Never underestimate the predictability of stupidity.
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trixxie
Member
Reged: 05/23/03
Posts: 130
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I have stayed at the same level of oxycontin for seven months with IR for B/T...with little or no tolerance issues.
I have not used morphine so no experience there...as the old saying goes...everyBODY is different.
good luck and take care
trix
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The truth shall set you free!
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Listvoer
Old Hand
Reged: 01/14/04
Posts: 411
Loc: New America
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If i'm not mistaken, orally administered morphine loses about 90% of it's "goodness" (for lack of a better word) in the stomach and that's why a person needing 150mg of the oral versions would (or at least, for the majority of people "SHOULD") only need around 15 MG in IV form. I have no idea why the IV version had such little effect on you, especially since the oral version worked, so who knows, it could have just been far too low a dosage or truly that drug reaction paradox that we hear about so often. Or, they could have given you the oh-so-worthless dummyoil, er, Demerol instead of morphine and that's why you couldn't stand it.  Interesting, anyway.
L
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Due to PM spam I rarely check mine so if you send me one, make sure to let me know...
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lovepink
Goddess
Reged: 01/01/02
Posts: 1476
Loc: NYC Metro Area
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Hi Pickledoo!
I've been prescribed both (not simultaneously) & found that even at the maximum dose, oral morphine was virtually worthless. Many if not most physicians willing to prescribe Schedule II narcotics seem to prefer the extended release versions - one brand of XR morphine I received was 90 mg. Avinza to be taken once daily. According to most narcotic dosage conversion charts, 90 mg. of oral morphine is equivalent to 60 mg. of hydrocodone. At the time, the pain I was in made Avinza a bad joke - I would have picked Oxycontin or Percocet in a heartbeat given the choice.
Good Luck.
LP
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Lovepink
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SuseCue
Member
Reged: 04/25/04
Posts: 169
Loc: Tampa, FL
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I take Avinza 120mgs and I find that it works pretty well for me. I also take Percocet 10 4x a day for BT if needed. Before I was taking the Avinza, the 4 Percocet a day was no where near enough. The Avinza definately helps me get by on the 4 Percocet a day.
I was taking Oxycotin first but I seemed to be moving up in mgs too quickly and I was concerned that I would max out too fast. It seemed like the more I took, the more I needed. So, I switched to the Avinza and just kept the Percocet for the BT.
Susie**
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Fighting for peace is like screwing for virginity.
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Pickledoo
Old Hand
Reged: 09/20/02
Posts: 409
Loc: New England
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Thanks for all your replies everybody! I was just curious because I have a source for morphine tabs and was just wondering because I have had the Oxy's and wanted to know how they differ. Just for the record, I HATED Oxy and was hoping I could find some relief in the morphine.
You guys ROCK!!!!
Big love,
Pickledoo
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night_shade
Threadhead
Reged: 08/26/03
Posts: 907
Loc: The State of Hockey
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Another factor to consider in the IV vs oral morphine problem with me was the amount of pain. The IV morphine was adminsitered for post-op pain (abdominal hysterectomy) and was wholly ineffective at whatever dose they gave me (I MAY be mistaken, but I believe it was somewhere around 20mgs/hour) AND I was concurrently receiving 100mgs/day of methadone for chronic pain at that time. Therefore, it could have been the methadone or the type of pain which made it useless for me as post-op analgesia.
My total daily dose of MSContin when that was my chronic pain drug was anywhere from 300-480mgs. I was also given standard Percocet for BT pain...3-4 tabs a day as needed.
So, it may not be such a weird experience after all?
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Never underestimate the predictability of stupidity.
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Listvoer
Old Hand
Reged: 01/14/04
Posts: 411
Loc: New America
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I think that might be your answer.. if you were taking that much pain meds on a regular basis and then the hospital switched you to just a 20mg drip I would think it would be like taking an aspirin for an amputation! If the docs didn't know about the methadone then they may have *really* underdosed you. Good luck, and hope that kind of situation never comes up again!
L
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Due to PM spam I rarely check mine so if you send me one, make sure to let me know...
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theborg
Board Addict
Reged: 10/20/02
Posts: 317
Loc: Boston
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As everyone has said here, Morphine via IV is much stronger than taken orally. Here is a conversion calculator you might find useful.
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I know in darkness I will find you giving up inside like me.
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nickiea
Stranger
Reged: 01/15/02
Posts: 4
Loc: AR.
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My pain doc started me on oxycontin first.I have severe disc disease.I had been on 40mg of the oxy 3x's a day when he changed it to mscontin 60mg 3x a day. I had been on the dose of 40mg 3x a day for about 2 years & it had been slowly losing it's effectiveness. I have had really good results with the mscontin other than I thought it was a little too strong at first & made me more drowsy than oxy. I had to have foot surgery recently & I've learned to tell them that due to the high dose of mscontin daily I do better with demerol post op. It is hard to get good pain control from surgery when you have a high tolerance due to long term use.
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IMSUSCOT1
Threadhead
Reged: 10/23/02
Posts: 892
Loc: usa
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Ask them to put you on a PCA, it stands for Pt. controlled anesthesia, it's a pump and instead of waiting for a nurse to give you a pain shot every 2-4 hours, you can give youself a dose every six minutes, it has a lock out so you can't give to much, they can load it with morphine or demerol.
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