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tone
Veteran
Reged: 06/29/03
Posts: 554
Loc: Chicago
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considering that if someone who never took an opioid before can take one and get euphoria, who's to say someone cant get dysphoria from taking naltrexone ?
just because you are not on an opioid at the same time you take naltrexone doesnt mean you cant get dysphoria from it, afterall, it is the exact oppisite of an opioid, an antagonist. It would block natural endorphins from being utilized. Many people who never took a drug in their life would probably go into a foul mood from taking naltrexone but the medical community ignores this and ackowleges euphoria from opioids.
so then who the heck would want to take naltrexone for things like alcoholism, boosting immune system, or staying detoxed from opioids? its bad for mood and mental wellbeing!
(I wonder if Naltrexone Withdrawl feels as good as opioid withdrawl feels bad)
Naltrexone-induced dysphoria
in former opioid addicts
by
Crowley TJ, Wagner JE, Zerbe G, Macdonald M.
Am J Psychiatry. 1985 Sep;142(9):1081-4.
ABSTRACT
Naltrexone treatment, used to prevent relapse among former opioid addicts, is reported to have an extraordinary rate of noncompliance. Since activation of opioid receptors produces a sense of well-being, naltrexone's blockade of these receptors might produce dysphoria, which could contribute to noncompliance among addicts under treatment. To test this hypothesis, the authors administered naltrexone to four men who had been free of opioids for 9 to 44 months using a 6-week, placebo-controlled crossover design. One subject dropped out with abstinence-like symptoms, and two others reported mild but significantly greater dysphoria during naltrexone administration. The results suggest that naltrexone may induce mild dysphoria long after addicts stop using opioids.
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prudence
Stranger
Reged: 08/23/03
Posts: 17
Loc: Florida
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Well put my friend!
Sorry if this is a little off topic. I was around during the height of the counterculture and even though I was very young, I have an older brother who had much influence on me. He has been schizophrenic since those turbulent days. Whether LSD was the cause, no doctor can say for sure. He has been prescribed Naltrexone for a drinking problem. I can verify from personal experience that Naltrexone does indeed put you in a foul mood, even if you are totally clean. The "establishment pigs" lied then, they are lying now (for instance, Marijuana is a Schedule 1 drug) and they will continue to lie from now until doomsday.
Please don't take this as an endorsement for drug use. The counterculture had many flaws and many wonderful people from those days are dead now and died well before their time. Three of my friends have committed suicide and their deaths correlate to some extent with drugs or at least to mental illness precipitated by LSD use.
Sorry for the rant. You can go ahead and censor me or if that doesn't happen, you all can write your venomous replies. It was very cathartic to write this. I have wonderful memories of that anomaly in time.
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tone
Veteran
Reged: 06/29/03
Posts: 554
Loc: Chicago
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sorry to hear about your friends, perhapes it wasnt just drug use but they were people who felt like they didnt belong here, or depressed? theres so many suicides, 3 times mroe than homocides, that its hard to link it completely with drug use even if they are on drugs. besides there also the factor of self-medication
you are right about the establishment pigs and it is strage how they would admit to opioids causing euphoria, but ignore something like naltrexone causing someone to be depressed or less able to experience any pleasure. they are also very ignorant about depression and continue to push dirty SSRIs and other drugs even if they dont work. the bioengineers even make an effort to design compounds that wont work good for depression because if something worked good it would have " abuse potential " so they target serotonin and other chemical mechanisms that may not be the cause of many depressions. the policy and paradigm has been pro-suffering weather its on purpose or due to ignorance or both. im surprised theres not more suicides than there already are
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