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Haven't used the Tosidrin but have used the Paracodina (also liquid DHC) from P24...DHC doesn't have much of an analgesic effect on me anyway but I thought the liquid was pretty decent. I believe its only about 10 mgs. DHC per ml so you'd really need about 6 ml (approx, 6 tsp.) if you wanted the equivalent of the typical 60 mg. DHC caplet.