gondola
Member
Reged: 10/27/02
Posts: 101
Loc: UK
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I've developed a high tolerance to zopiclone, meaning that I can take 4 tablets and still not get to sleep. No withdrawal problems, just a tolerance. Does anyone know if this tolerance means that I will also have an equivalent tolerance to Ambien? Or do they work on different receptors, perhaps. Any help or advice would be much appreciated!
Thanks,
Gondola
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trex
Journeyman
Reged: 01/04/04
Posts: 70
Loc: Australia
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Ambien and Imovane(zopiclone) are in the same family!
However I don't Know if one will increase the effectiveness of the other!!
Try using something in a different family eg. Restoril, lorazepam ect
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gondola
Member
Reged: 10/27/02
Posts: 101
Loc: UK
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Quote:
Ambien and Imovane(zopiclone) are in the same family!
However I don't Know if one will increase the effectiveness of the other!!
Try using something in a different family eg. Restoril, lorazepam ect
I'd rather not be taking a "genuine" benzo every night though, do avoid dependency..... I was just wondering if the fact that I now have a high tolerance for zopiclone means that I will "straight away" have an automatic high tolerance for Ambien. Not sure how they are related to each other as drugs, if you see what I mean.
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trex
Journeyman
Reged: 01/04/04
Posts: 70
Loc: Australia
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Imovane(zopiclone) is stronger! So I'd say it'll help you for a while! 
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tone
Veteran
Reged: 06/29/03
Posts: 531
Loc: Chicago
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drugs that have the same or very similar mechanisms usually cause tolerance to each other. its known as 'cross-tolerance'. On sites like rxlist.com and drugs.com you can get the monograph of these drugs and read about their pharmacological mechanisms
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trex
Journeyman
Reged: 01/04/04
Posts: 70
Loc: Australia
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I know from personal experience after using ambien for quite some time! That Imovane(Zopiclone) was not seriously affected!!! 
I hope this helps!
PS.IF YOU LOOK IN MY POST HISTORY FROM A FEW DAYS BACK!
IVE SUGGESTED TO SOMEONE ABOUT ROTATING MEDS!!THIS WAS GIVEN TO ME AND WORKS WONDERS IF YOU HAVE BAD INSOMNIA PROBLEMS!!
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trex
Journeyman
Reged: 01/04/04
Posts: 70
Loc: Australia
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AND I QUOTE MYSELF,
I empathise totaly!!Having been a cronic insomniac for years I've found that I become tolerant to almost any drug fairly quickly!!!
I now alternate between a range of drugs trying not to use a particular one more than once or twice a fortnight!!
Remember that quite a few drugs are from the same family (eg. benzos) so even when you only take each variety once or twice a fortnight you can still develop a tolerance!!
I use this formula:
day1: temazepam(2*20mg gel caps or 2 30mg tabs)
2: zopiclone(2*7.5mg tabs)
3: lorazepam(2*2mg tabs)
4: phenobarbital(2*60mg tabs)
5: stillnox(Ambien)(2*10mg tabs)
6: 2*10mg valiums and 2*sleepaids(OTC in Australia)
7: *NOTHING*
8: temazepam(2*20mg gel caps or 2 30mg tabs)
9: phenobarbital(2*60mg tabs)
10: 2*10mg valiums and 2*sleepaids(OTC in Australia)
11: zopiclone(2*7.5mg tabs)
12: lorazepam(2*2mg tabs)
13: stillnox(Ambien)((2*10mg tabs)
14: *NOTHING*
I have been using this formula for a couple of months now however if I find a particular drug is not working Ill stop taking it for a couple of weeks! There are numerous alternative sleep aids! Combining valium or klonopin with a mild OTC sleep aid can sometimes work!
I never take the Phenobarb if I need to be clear minded the following morning!
Surprisingly I find on the rest night where I take nothing I seem to sleep alright!!
I HAVE BEEN A CRONIC INSOMNIAC FOR MOST OF MY LIFE AND AFTER NORMISON(20MG GEL CAPSULE TEMAZEPAM) WAS MADE DIFFICULT TO GET I COULDN'T SLEEP PROPERLY FOR WEEKS!!!
A FELLOW DB MEMBER RECOMMENDED A SIMILAR SYSTEM TO THIS AND IT SEEMS TO WORK WELL!!
EXPERIMENT WITH WHAT WORKS FOR YOU!! IF A DRUG THAT USED TO WORK STOPS DOING SO GIVE IT A REST FOR A WHILE AND IT WILL PROBABLY WORK AGAIN!!
hOPE THIS HELPS SOMEONE AS IT HAS HELPED ME!!
GO WITHOUT A GOOD NIGHTS REST FOR A WHILE AND YOU FEEL LIKE A WALKING ZOMBIE!LIKE YOU'VE LOST THE PLOT!!
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gondola
Member
Reged: 10/27/02
Posts: 101
Loc: UK
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Thanks to all for the advice I intend to start rotating meds, but was worried that it might not be the same as "rotating" if they worked in exactly the same way. But I shall order some Ambien with confidence now!
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