knighthawk
Stranger
Reged: 12/02/03
Posts: 15
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I'm not sure if this is the right place to post, I'm new to the board so please forgive me. If anyone know's what "Buprenorprine HCl" is I'd really appreciate the info. I looked it up on rxlist.com but it wasn't listed. Thanks.
-knighthawk
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Traditional nationalism cannot survive the fissioning of the atom. One world or none.
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Whatsnew
Enthusiast
Reged: 09/27/03
Posts: 205
Loc: S.E. USA
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Temgesic.
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DBs member since Feb. '03
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hoop123
Enthusiast
Reged: 12/14/01
Posts: 258
Loc: New York
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Buprenorphine is a synthetic opiate with agonist/antagonist properties. In a sense it means if you were taking traditioniol opoids, ie: Norco,for an extended period of time and you took Buph you could be sent into immeditate withdrawl from the Norco.
I had had it perscribed in the past under the brand name Buprenex for the treatment of cronic pain. It is a narcotic pain reliever for moderate to severe pain. Plus as stated above , cannot be taken with traditional opoids.
Today it is currently used for the treatment of opiate withdrawl. It goes under the brand mane Subtex and Suboxone. Thats probaly why you had trouble researching it. It come in sublinguil form and helps with the withdrawl symtoms. It used to be an FDA Class V drug but has since been changed to class III. Only Doctors trained in the dispensing and treatment of opoid withdrawl are allowed to prescibe it.
I thought it was a wonderful medication for cronic pain because it lasted long, had very little tolerence build up and was very easy to come off of.
I know this is a lengthy post and I apologize. Because I had taken it before I found it very difficult to explain it in a short manner. I hope this info helps. Thank you for youre time and consideration.
Best Regards,
Hoop
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meowsie
Member
Reged: 12/16/03
Posts: 168
Loc: MA
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This may be a silly question but how can something that causes withdrawel also relieve it? If you ran out of norco and took this it would cause wd, but at the same time make you feel better, is that how I understand it? So what is the problem with it causing wd if it relieves it? I have heard of this before, I just didn't understand it, and I still don't. if I wanted to go off norco, could I just take this med and feel ok? where do you get it, IOP's??
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hoop123
Enthusiast
Reged: 12/14/01
Posts: 258
Loc: New York
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Being Buph is an agonist/antagonist if you were currently dependent on Norco and took Buph the antagonist would put you into withdrawls. If you were already having withdrawl symptoms from Norco it would alleviate them. I am not a Pharmacist so I can not speak of the pharmakinetics of the med. I only know if you took Buph and Norco together the effects of Norco would be blocked by the antagonist in Buph. Most opoids I believe are agonists.
So to properly take Buph as a tool for detox it would probably be best to take the Buph about 6-8 hrs after you're last Norco (opoid) dose. Remember I am not a Pharmacist. These are just approx. It is then that you will feel the effects. It will lesson the w/d symptoms, etc. Slowly decreasing the Buphs quantity will bring you closer to detox.
As far as optaining the med, the previous poster mentioned the international brand name Temegesic. International ops (Mexican), have it available sublinguily in .2mg doses and some have it available in ampules at .3 mg dodes/ml. The injectible can be taken under the tounge, do not swallow, with good effect. Or it can be injected IM. Im not sure which op is the best for this you may want to check the IOP boards. Hope this helps. I am doing the best I can since I am no a Pharmacist.
Best Regards,
Charlie
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cloudy
Member
Reged: 11/07/03
Posts: 163
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There are two types that are marketed for opiate withdrawel. Subutex and Suboxone. If you do a search either here or on a search engine you will find much more info. Subutex is the one without the naloxone in it. This one will not give you wd symptoms. The suboxone will only if you are dependant on opiates and if you take a large dose of it. This drug was allowed to be used in addiction recovery in late 2002 I believe. Doctors who plan on weaning patients off of opiates (including methadone) have to get a special license (its called some sort of letter) to be able to treat patients. They also are only allowed to a limit of 30 patients total for treating at any given time. If someone gets off, they are allowed one new patient... There are a few websites that can give you some very great info. Just do a search. There is also a doc locator on the governments website.
Temgesic is the same as the subutex and is available from IOP's but it looks as though they are only available in 2mg (sublingal) tablets and possibly liquid???. The tablet are placed under the tongue.
I think if a US DR prescribes, they come in 8mg sublingual and possibly other mg's. However, thats all I remember about strengths. So, if this is the avenue, you are looking to go down, you should check into getting a DR, therefore you are monitored while taking it (if anything arises). Plus you could run into all kinds of issues ordering from an IOP. Nevermind that it is illegal 
anyway, I thought I would give you the information I remember reading. It is very interesting when you read about how the receptors in your brain work and how this and other opiates actually work. check it out!
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night_shade
Threadhead
Reged: 08/26/03
Posts: 907
Loc: The State of Hockey
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The Temgesic is available in 0.2mg and 0.3mg sublingual tabs (wasn't sure if you just forgot the decimal point or not!)
Buprenorphine works differently than other agonist/antagonists like Talwin/Nubaine/Stadol because it SLOWLY disassociates from receptors, thereby not precipitating withdrawal syndrome in opiate-tolerant patients like Stadol or Nubaine will.
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Never underestimate the predictability of stupidity.
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Disciple
Member
Reged: 12/11/03
Posts: 113
Loc: Deep South-GA
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I've read somewhere this is a strong pain reliever as well?
Does anyone have experience along this line? Sure would be better than being concerned about tolerance levels and possible addictions. BLESSINGS 2 U ALL...Disciple
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The kindest words ever spoken are harsh words left "unsaid". A SOFT ANSWER TURNETH AWAY WRATH: BUT GRIEVIOUS WORDS STIR UP ANGER. PROVERBS 15:1
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zeuzjuz
Pooh-Bah
Reged: 12/16/01
Posts: 1155
Loc: the milky way
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http://www.buprenorphine.samhsa.gov/
Provides MUCH more info than could ever possible be posted here.... This is a very complex medication, in it's form, it's usage, it's method of action, it's legal status, and the regulations put forth in the U.S on prescribing it. There are so many variables with this medication, that in my opinion, it is imperative to be very well informed about it, before you decide you want to try it. There is tons of info on the site I posted, and also at www.opioids.com (They have a huge buprenorphine section , lots of info)
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//zeuzjuz
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zeuzjuz
Pooh-Bah
Reged: 12/16/01
Posts: 1155
Loc: the milky way
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Quote:
Sure would be better than being concerned about tolerance levels and possible addictions
Buprenorphine IS an opioid (although it has partial antagonist properties) - So this is really not the case. Tolerance and addiction/dependance are still very much an issue with Buprenorphine. It is widely abused (believe it or not) all throughout Europe and Asia.... (Usually by using it in other ways than specified ie: injection, etc) It is a good pain reliever, the antagonist properties block euphoria (which is one reason it helps with detoxification - you don't get euphoria - therefore, less addiction potential) - It is good for getting off of other opioids - BUT it is STILL an opioid - so you are not safe from the possibility of addiction or tolerance while using it. It is a miracle medicine for weening off of stronger opioids, but many people become addicted to Buprenorphine just like they were the other opioids, ie: trading one addiction for another... Also, it DOES build tolerance, just as all other opioids do. Although not at the same super-fast rate.... I think this has to do with it being a partial antagonist.,
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//zeuzjuz
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zeuzjuz
Pooh-Bah
Reged: 12/16/01
Posts: 1155
Loc: the milky way
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Think of it as a BETTER (and less addictive) methadone....
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//zeuzjuz
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buey
Old Hand
Reged: 01/15/03
Posts: 453
Loc: USA
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Our pet guinea pig fell and broke its top two teeth. The teeth ended up jammed into the lower gums. He was a mess. The vet had ot cut down all four front teeth and then gave him this med and it really mellowed the little bugger out. I was very happy that the vet was compassionate enough to give him some pain meds. While on it, he was able to eat and drink. When the dose would start wearing off, he would refuse food and water, so I know this was a huge help to him. He did sleep most of the day, but at least he was out of pain. The effects lasted for a good 12 hours too. I think this is a great pain med. Never took it myself, but I saw the good it did for the little pig.
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Disciple
Member
Reged: 12/11/03
Posts: 113
Loc: Deep South-GA
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Zeuzjuz,
Thank you so much for the information! I really do value your opinion. Members just as you provide much comfort that I'm not stumbling in complete darkness.....BLESSINGS 2 U...Disciple 
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The kindest words ever spoken are harsh words left "unsaid". A SOFT ANSWER TURNETH AWAY WRATH: BUT GRIEVIOUS WORDS STIR UP ANGER. PROVERBS 15:1
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