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night_shade
Threadhead
Reged: 08/26/03
Posts: 907
Loc: The State of Hockey
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Zelnorm Pharmacology
According to the package insert, there is no reason the active ingredient tegaserod maleate shouldn't work the same in both sexes. However, studies done pre-FDA approval, showed that only women seemed to respond favorably to Zelnorm.
Honestly, I believe a man suffering from IBS could definitely give it a try.
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Never underestimate the predictability of stupidity.
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Sky_Queen
Fly Girl
Reged: 12/03/02
Posts: 1962
Loc: Texas
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I asked my doctor that very question Opie - and she didn't have an answer for me.....I'm going to ask my brother who is a pharmacist, just because I'm curious. Opie - do you have IBS too?
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Opie_Yates
Old Hand
Reged: 08/11/03
Posts: 470
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Quote:
I asked my doctor that very question Opie - and she didn't have an answer for me.....I'm going to ask my brother who is a pharmacist, just because I'm curious. Opie - do you have IBS too?
No, Sky Queen, just irratable 41 year old man syndrome. The IBS is someone else in my life.
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I'm not a doctor, I just play one on a message forum!
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lemongrass
Board Addict
Reged: 09/23/03
Posts: 361
Loc: IL
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Quite honestly, I don't see why this is such a disgusting topic. I mean, we all have bowels and it is a natural act. Animal and man both do it, so why is it disgusting exactly, other than the odor emitted in the process? To me, it is a private act we all prefer to perform alone, but why should it be labled disgusting when we discuss it?
I once had some descriptions of my excrements that I thought needed to be shared with my gastro and he acted appalled, stating, "Now that was a little more information than I needed." For crying out loud, he was my friggin' doctor and I shouldn't have been made to feel like I couldn't share the strange and unusual with him, where my health is concerned.
I have to ask this question. If there are no built toxins in our bodies, then riddle me this.
Before 1998 I never had an allergy to anything...well, other than bee stings. But never to foods or medicines. One fine day, after having my gall bladder removed, it was discovered I was allergic to sulfa. From that point on, I started experiencing Severe Allergic reactions daily. It was recurring for 4 months!!! I came close to dealth numeros times and the allergist labeled it Idiopathic Anaphylaxis. In other words, they couldn't figure out what I was allergic to. There were no patterns and nothing mathced up when it came to those episodes.
One of the questions I posed to my gastro was if it has something to do with my liver not processing the things I ingested properly. Of course he dismissed this, as doctors usually do sinc they're not too fond of us patients grandstanding them in any way, shape, or form.
I tried researching this topic but to no avail. But one thing did occur to me, just everything we put into our bodies is accumulative. If there was an accumulative agent within our bodies, what's so difficult to believe that something poisonous and toxic wouldn't develope?
I've got to tell you, whenever I have one of those allergic reactions, it literally feels like my body is full of toxins and trying to rid of them. I become violently ill and it makes me wonder just how far my liver damage has progressed. I mean, after all, if the liver is not functioning properly, now can we expect it to transform certain meds and other ingestibles into the "good stuff"?
JMHO
lemongrass
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yawkaw3
Pooh-Bah
Reged: 03/22/03
Posts: 1193
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What exactly do you mean by "toxin"? A bacteria? A virus? Toxin is a very vague term.
Feces doesn't accumulate as much as you might think- it certainly can happen, and is something that needs to be watched in people who are chronically constipated (especially in people on round-the-clock opioids)- but the typical person does not have to worry about that. Our bodies have handled getting rid of feces just fine for thousands of years.
You do not need to make a bowel movement many times per day to prevent this from happening- there's nothing wrong with making good, frequent bowel movements and that's why some doctors (generally PCP's, a gastro would tell you it isn't a huge deal) would tell you that, but it's not harmful if you don't.
If you did have too much accumulation, a high fiber diet or laxatives would solve the problem. You don't need a colonic. And even if you did have too much feces accumulating- why is there no proof it turns toxic? It's not that it's hard to believe, lemongrass, you make a good point, it's that we have no proof after much study on the subject.
The people who sell colonics make a fortune off people mistakenly believing in these toxins. But why haven't we found any of them? How come none of them can be identified? No one ever mentions a specific toxin. Where are they, if they are so toxic and present such a big problem- they're nowhere to be found ANYWHERE in the circulatory system, or any other organ for that matter.
If you did have reason to suspect there was some sort of "toxin" or harmful bacteria/virus/etc. down there, you should go to a doctor who can do a stool sample and prescribe the appropriate antibiotic. That is the way to treat "toxins," if it didn't work, modern medicine wouldn't rely on it as a first-line treatment.
If your liver didn't process things you ingested properly, I'm not sure why it would cause anaphylaxis? I guess it could somehow convert whatever you ingested into an antigen that might relase some sort of mast cell mediator (histamine, leukotrine, etc.), but I don't think that is very likely. Allergy/Immunology is not my thing, I only know the basics, but I don't understand what the liver would have to do with it.
When you have those allergic reactions, your body is having a full-swing inflammatory response. It would definitely feel like there are some sort of toxins, but really it is your body's own chemicals that are making you feel that way, the toxin (which is an antigen of some sort in this case) only started the reaction; the reason you feel the way you do during it is because of a huge release of histamine/leukotrine/and a bunch of other chemicals.
But regarding the liver damage, what would that have to do with it?
I'd be interested in talking about this more with you if you want, I can't help you figure out the idiopathic anaphylaxis, but if you want me to explain why the liver is not the culprit here and how anaphylaxis really works, I'd be glad to discuss it with you, PM or on here.
-yawkaw
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Firefairy
Member
Reged: 11/26/03
Posts: 147
Loc: Mississippi
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Ok, so maybe disgusting was not quite the word I was looking for. How about graphic?
Over the last ten years I have gone from being allergic to nothing but poisen ivy to multiple allergies, sometimes not being able to even tell what the reaction is to. My rheumatologist said this is a normal occurance in people who have lupus. She says it has nothing to do with the fact that I have IBS with constipation. The malfunction of the immune system that causes new and multiple reactions has a tendency to happen to people who are diagnosed with: lupus, fibromyalgia, rheumatoid arthritis, and, oh, about six other related conditions/diseases I cannot spell right off the top of my head and don't feel like looking up. I will if anyone wants me to, though.
I have noticed though, that most of my migraines do coincide with me being constipated. I am always open to new medical ideas, if a little dog that looks like a rat produces a dander that is a natural medication for asthma, who know what else is true.
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night_shade
Threadhead
Reged: 08/26/03
Posts: 907
Loc: The State of Hockey
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Firefairy-all the conditions you describe are auto-immune (well, I don't know about fibro...) diseases where your own immune system starts attacking itself for whatever reason. I couldn't tell from your post whether you believe the toxins thing or not.
I have RA and my understanding of it is that my own immune system is attacking my cartilege and bones. Not that my immune system is reacting to these mysterious toxins.
I ran over a hornet's nest when I was a kid and was stung dozens of times, ever since I have had severe allergic reactions to any hymenoptera (including ants) bites/stings, requiring a 3-season carrying of an epinephrine injection.
It is not uncommon at all for adults to develop allergies. Sometimes things such as stress, illness and other changes in our body chemistry might affect how our bodies deal with things like medications, pollen, stings etc. And MANY, MANY times people incorrectly diagnose as an "allergy" something which is NOT truly an allergy. For example, throwing up and feeling cruddy after taking codeine is most likely NOT an allergy. TRUE allergic reactions involve rash, hives, and sometimes anaphlaxis--due to the over-production of histamines in our bodies at the time. Getting an all-over rash that makes you want to rip your skin off from itching so bad is an allergic reaction to codeine (which I have had--requiring an ER visit--and developed as an adult after a pretty good dose of it) whereas vomiting and feeling "weird" is probably just an adverse reaction. Not the same thing at all.
Just wanted to put my 2 cents in here as I am VERY, VERY skeptical of the whole toxins theory and, while I am not trying to dissaude anyone from believing in it, I just hope people research any alternative medical procedure before trusting in it. Many of them have documentable positive results (like acupuncture) while many of them do not (colonics.)
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Never underestimate the predictability of stupidity.
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Firefairy
Member
Reged: 11/26/03
Posts: 147
Loc: Mississippi
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The conditions I am talking about are mostly auto-immune, some are not. They are all part of a large group that some doctors refer to as "connective tissue" disorders. They share some of the same symptoms and frequent misdiagnosis seems to be another common factor.
I don't think toxins have anything at all to do with allergic reactions or auto-immune disorders. In my current opinion colonics are just a very expensive enema. I am, however, always ready to consider new medical evidence if any is ever found. Things that were once considered medically sound have sometimes been proved bogus, things that were once considered old wives tales have sometimes been proven grounded in solid science. Medicine is an always evolving and changing thing.
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prettyday
Threadhead
Reged: 02/09/03
Posts: 924
Loc: Coastal Sage Scrub
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Quote:
No, Sky Queen, just irratable 41 year old man syndrome. The IBS is someone else in my life.
Opie, I laughed out loud so hard!!!!!and muffled it because my colitis is sleeping in the next roooooommmm... 
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First they ignore you, then they laugh at you, then they fight you, then you win.
- Mahatma Gandhi
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NJ_Hoss
Enthusiast
Reged: 10/29/03
Posts: 263
Loc: USA
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My first wife had three ethnic dishes that could clean the collective colons of an entire dinner party in 6 minutes flat.
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