how serious of a seizure risk it is varies from person to person. the two factors are how overall prone a person is to one and how well a person metabolizes tramadol. tramadol its self is what can cause seizures, its metabolites are much more benign.

this med should always be started at a low dose and feeling funny or memory blurred calls for lowering the dose and consulting a doctor.

to reduce changes of seizure do not take these meds with tramadol: Antidepressants, MAOIs, CYP2D6 Inhibitors. Consult with doctor if taking other CNS drugs.

List of CYP2D6 Inhibitors ( Source ): amiodarone, buproprion, celecoxib, chlorpheniramine, chlorpromazine, cimetidine, citalopram, clomipramine, cocaine, doxorubicin, escitalopram, fluoxetine, halofantrine, levomepromazine, methadone, moclobemide, paroxetine, quinidine, ranitidine, haloperidol, ritonavir, sertraline, terbinafine