Common Trademarks:
Anexsia®, Hycodan®, Hycomine®, Lorcet®, Lortab®, Tussionex®, Tylox®, Vicodin®, and Vicoprofen®.

Hydrocodone Photos

Background Information:
Hydrocodone is an orally active analgesic and antitussive Schedule II narcotic that is marketed in multi-ingredient Schedule III products. Hydrocodone has an analgesic potency similar to or greater than that of oral morphine.

Common Dosages:
In its most usual product forms hydrocodone is combined with acetaminophen (Vicodin, Lortab), but it is also combined with aspirin (Lortab ASA), ibuprofen (Vicoprofen), and antihistamines (Hycomine). Both tablet and liquid forms of hydrocodone are available (e.g., Tussionex)

Three dosage forms are typically found (5, 7.5, and 10 mg)

Hydrocodone 10/325
Hydrocodone 10/500
Hydrocodone 10/650
Hydrocodone 7.5/750
The 10 in the "10/325" is the 10 mg of hydrocodone and the 325 is 325 mg of acetaminophen.

Side Effects:
Hydrocodone side effects include but are not limited to:

anxiety
constipation
decreased mental & physical performance
difficulty breathing
difficulty urination
dizziness
drowsiness
dry throat
emotional dependence
exaggerated feeling of depression
extreme calm (sedation)
exaggerated sense of well-being
fear
itching
mental clouding
mood changes
nausea & vomiting rash
restlessness
sluggishness
tightness in chest
Drug Abuse and Dependance:

Hydrocodone bitartrate and acetaminophen tablets are subject to the Federal Controlled Substance Act (Schedule III).

Psychic dependence, physical dependence, and tolerance may develop upon repeated administration of narcotics; therefore, hydrocodone bitartrate and acetaminophen tablets should be prescribed and administered with caution. However, psychic dependence is unlikely to develop when hydrocodone bitartrate and acetaminophen tablets are used for a short time for the treatment of pain.

Physical dependence, the condition in which continued administration of the drug is required to prevent the appearance of a withdrawal syndrome, assumes clinically significant proportions only after several weeks of continued narcotic use, although some mild degree of physical dependence may develop after a few days of narcotic therapy. Tolerance, in which increasingly large doses are required in order to produce the same degree of analgesia, is manifested initially by a shortened duration of analgesic effect and subsequently by decreases in the intensity of analgesia. The rate of development of tolerance varies among patients.

Drug Interactions:

Patients receiving other narcotic analgesics, antipsychotics, antianxiety agents, or other CNS depressants (including alcohol) concomitantly with hydrocodone and acetaminophen tablets may exhibit an additive CNS depression. When combined therapy is contemplated, the dose of one or both agents should be reduced.

The use of MAO inhibitors or tricyclic antidepressants with hydrocodone preparations may increase the effect of either the antidepressant or hydrocodone.

The concurrent use of anticholinergics with hydrocodone may produce paralytic ileus.

Acetaminophen with hydrocodone is used for the relief of moderate to severe pain. Inform your physican if you are pregnant or nursing. This medication may cause dizziness, drowsiness, or blurred vision; use caution while driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking acetaminophen with hydrocodone. This medication may be habit forming. Withdrawal symptoms may occur after you stop taking acetaminophen with hydrocodone. Inform your physician if shortness of breath or breathing difficulty occur. May cause nausea, vomiting or constipation; notify your physician if these occur. May be taken with food if GI upset occurs.

Note: As of 12/2002 the following strength combinations are manufactured by Watson Pharmaceuticals, Inc. :

HYDROCODONE/APAP TABS 10/325 CIII 100s
NDC: 00591-0853-01

HYDROCODONE/APAP TABS 10/500 CIII 100s
(Compare to Lortab ®*)
*Lortab ® is a registered trademark of Whitby
NDC: 00591-0540-01

HYDROCODONE/APAP TABS 10/650 CIII 100s
(Compare to Lorcet 10/650 ®*)
*Lorcet 10/650 ® is a registered trademark of Forest Pharmaceuticals
NDC: 00591-0503-01

HYDROCODONE/APAP TABS 2.5/500 CIII 100s
(Compare to Lortab ®*)
*Lortab ® is a registered trademark of Whitby
NDC: 00591-0388-01

HYDROCODONE/APAP TABS 5/500 CIII 100s
(Compare to Vicodin ®*)
*Vicodin ® is a registered trademark of Knoll Pharmaceutical
NDC: 00591-0349-01

HYDROCODONE/APAP TABS 5/500 CIII 500s
(Compare to Vicodin ®*)
*Vicodin ® is a registered trademark of Knoll Pharmaceutical
NDC: 00591-0349-05

HYDROCODONE/APAP TABS 7.5/500 CIII 100s
(Compare to Lortab ®*)
*Lortab ® is a registered trademark of Whitby
NDC: 00591-0385-01

HYDROCODONE/APAP TABS 7.5/500 CIII 500s
(Compare to Lortab ®*)
*Lortab ® is a registered trademark of Whitby
NDC: 00591-0385-05

HYDROCODONE/APAP TABS 7.5/650 CIII 100s
(Compare to Lorcet Plus ®*)
*Lorcet Plus ® is a registered trademark of Forest Pharmaceuticals
NDC: 00591-0502-01

HYDROCODONE/APAP TABS 7.5/750 CIII 100s
(Compare to Vicodin ES ®*)
*Vicodin ES ® is a registered trademark of Knoll Pharmaceutical
NDC: 00591-0387-01

HYDROCODONE/APAP TABS 7.5/750 CIII 500s
(Compare to Vicodin ES ®*)
*Vicodin ES ® is a registered trademark of Knoll Pharmaceutical
NDC: 00591-0387-05

MAXIDONE™ CIII 10MG/750MG 100s
(Hydrocodone Bitartrate and Acetaminophen 10mg/750mg Tablets)
NDC: 52544-0634-01

NORCO® 5MG/325MG CIII 100s UD
(Hydrocodone Bitartrate and Acetaminophen Tablets)
NDC: 52544-0913-48

NORCO® 10MG/325MG CIII 100s
(Hydrocodone Bitartrate and Acetaminophen Tablets)
NDC: 52544-0539-01

NORCO® 10MG/325MG CIII 500s
(Hydrocodone Bitartrate and Acetaminophen Tablets)
NDC: 52544-0539-05

NORCO® 5MG/325MG CIII 100s
(Hydrocodone Bitartrate and Acetaminophen Tablets)
NDC: 52544-0913-01

NORCO® 7.5MG/325MG CIII 100s
(Hydrocodone Bitartrate and Acetaminophen Tablets)
NDC: 52544-0729-01