I am not Negrodamus by any means,but i forsee and predict this to be a flame-infested thread if there ever was one.So,i'll go first, i guess.

I have had every brand of hydrocodone that they make,of course,the different strengths make a difference.But,if you have a 10/500 mally lortab and a 10/500 Watson,they differ so much,that it should be against the law or something,honestly! This is just one example of comparison,but the reason for such difference is the BUFFERS! It took me years to find out the truth.(questioning literally 100's of pharmacists,and hours of internet research)It wasn't util i found a pharmacist that was a chronic pain sufferer that actually had in-depth knowledge of pain medication,or at-least was the first to admit it.

Also,something else i found to be the truth,and i agree totally.He told me that a 7.5/750 Vicodin was stronger than the 10/325 Norcos i was being prescribed at the time.Had my doc switch me,guess what,they were stronger and lasted longer,much longer! Went from 5 norcos a day to 4 vikes a day.Only thing i increased in was APAP,from 1625mg to 3000mg,still under your daily allowance by 1000mg.

That's why when i see everybody switching to Norcos to avoid Tylenol,i just don't see how they are getting adequate relief without self-medicating(or increasing there dose).Which the truth is they are not increasing to get the extra Hydro which they believe,it is only until they reach the adequate amount of Tylenol to amplify the Hydro that has already been ingested.

P.S. Apologize to ramble,my point is that different brands do make a difference,but also correct Hydro/Tylenol(apap) make a difference as well.

This outta be an interesting topic!

"PIECE IN THE MIDDLE EAST"