Almost all the states with electronic prescription monitoring use it only for C-IIs. Hawai'i's program does not limit them to C-IIs, on paper at least, so the Dept. of Public Safety there can add any controlled substance to the list of meds they monitor ... but they're supposed to only add drugs that are a public health and safety concern, such as any drug that's widely abused.

Scrip monitoring means that the pharmacy in a state with that program has to report all fills that meet the state requirements to their own state program. It doesn't matter where the customer is located. It depends on where the pharmacy is located. Let's assume that someone is using multiple OPs and getting multiple overlapping fills from pharmacies located in a state with monitoring. All those fills will be reported to that state. Then, if the state monitoring authorities there think you might be violating a law, they can inform local law enforcement where you live.

The scrip monitoring programs take away some of your privacy rights. Pharmacies in those states are required to give your (normally) confidental info to law enforcement even if the scrips are valid and confirmed by the doctor's office.