That's a good question, LPR. Normally there are several seizure threads active at any given moment around here, and topics like this are discussed. And I don't think anybody has ever definitively stated that there is a greater seizure risk if you get your orders sent to a PO Box.

It's not the Postal Service that screens and seizes overseas packages, it's the good old US Customs.

I don't get package delivery where I live, so I have to pick up most parcels at the Post Office. Frankly in my experience the postal clerks are much less interested in what I get in the mail than, for instance, the Fedex guy.