Let's say that an original paper script with two refills is valid for "X" amount of days before it expires. Does every day you wait to fill it subtract from the life of the refills? I don't care what schedule or class the drug is, just if a given expiration date on ANY original paper script takes away from the refill life if filled late? OK, I know what you're gonna say about WAITING to fill a script of 10/500's, but I'm only posting about THEORETICAL script life and refills and not reality. As for reality, all I know is that I usually ALWAYS comply with the "Discard By" date. That is to say, define "discard". If "discard" equals "gone" then my meds are usually "that" well in advance of the well meaning and printed on the bottle expiration date. I don't really map it out on my palm pilot, but it just kinda usually ends up like I did. How 'bout you folks?