I've taken accutane, and I agree that anyone taking it needs to be monitored. Before the doc wrote my prescription, I was given a book (not pamphlet), about all of the nasty potential side effects (including such pleasantries as organ and tissue damage, severe depression, cerebral edema whem combined with certain medications...). It did, however, work wonders for my face; after a decade of cystic acne, I haven't had a single "zit" since May!!!