Ok... My doc tried to sell me on Lexapro stating it is the greatest thing out on the market now. I asked him if it would stop panic attacks like Xanax and he stated...'Well, no but it will eventually erradicate a majority of the symptoms of anxiety." Umm... That's not what I was asking him. Needless to say, I took him up on his samples and received a script for it back in Sept. '02 - think that's when it was approved by the FDA. The way it's been explained to me is that Lexapro is identical to Celexa, only the drug companies have isolated the isotopes in Celexa and enhanced the SSRI to eliviate some of the side-effects with Celexa. If you're male and have been on Celexa for a number of years, you'll know what I mean. I'll have to agree that Lexapro did eliviate some of the side-effects of the older Celexa brand - BUT it does nothing for panic disorder or anxiety, IMO - just helps Chronic Depressive Disorder like Celexa did. So I called my local pharmacist and asked him if there was any 'potential' drug interactions with co-dosing Lexapro and Xanax. He stated "No, that they could be taken together - however warned that drowsiness may be increased". That was never the case for me though. You can always call any Eckerds or Walgreens and ask to speak to a pharmacist about drug interactions. Good luck.