It is my understanding that the 40mg disks are the same as the 10mg tabs made by many companies. The disks will dissolve faster in your stomach, thus making a faster approach to the small intestines, but methadone by its nature is a long-acting narcotic. I am prescribed 80mg's of the 10mg "methadose" tabs per day but I DO NOT like to take that many. I take as little as I can to get by because it makes me groggy, gain weight, constipated, bloated, etc. But it's better than the roller coaster Hydro ride. It's just too easy to buy hydros, which aren't really meant to be used long-term for most people.