rns67, you're right, Ultram may have been originally marketed because of it's anti-depressant properties, but once they found that there were significant pain killing actions associated with this medicine, the developers switched gears and Ultram became marketed as a pain killer (it was originally developed in 1977 in Germany). http://opioids.com/tramadol/tramadol.html

(I can look up where I read the information from anti-depressant to pain killer -- it was about 6 or so months ago that I saw it).

Corrie