Kimbell-1, as far as Norco 10/325 and Watson's 10/325, they are both manufactured by Watson Laboratory. The Watson's are just the "generic" for Norco. Personally, I have found little difference in how they work for me. There was a brief period, not long ago, where many people were complaining about the "potency" of the generic Norco, which are Watson 10/325. I hope this helps some b/c I'm not an expert on this but I wanted to assure you that if you want to save some $$$, the Watson's Hydro's work just about the same IMO. Take care!