If you take the meds for 6 days straight , skip the seventh day , and go back to six full days again, you will build a tolerance. Your body will get used to not having it on the 7th day , and adjust. But unfortunately, just skipping one day a week, wont really slow the tolerance down that much. ( everyones body chemistry is different, but most likely it wont help too much ) Good luck

Tansun