Don't see the connection with a holiday and an anti-diarrhetic. Could someone explain this one to me? The only thing that helps me are lots of nsaids (very bad for liver and hypertension) and benzos. I do get mild diarrhea that lasts about a day but whats the big deal. The worst for me is pain (even my skin hurts),insomnia and restless leg syndrom. This is after taking hydro almost constantly for 4 years (30-80 mg a day.)