Hi..I take a 'Holiday Break" kind for a week or so every 30 days but I am still on the derigesic patch (50ug/h) so I guess I really don't think it's a total break... ...I am really not sure how to take a break from that but am going to ask my PMD doc next week about it...I am putting on my patch every 48 hours ..but on my "break" I wait the full 72 wich was what I started on..doc increased it cause it did't work...but I find Soma really helps me..when I am going through this. Sleep is the best thing for you and that is VERY hard to come by at the 1-3 day stage..you just have to be carefull on the soma so you don't take one for the other...so good luck..by now you should be feeling better...I have a question on another thread but will wait an answer I just wanted to chime in and say first..."Happy Easter" for those whom celebreate and good luck Kathy...love reading your posts...keep it up and your doing a great job today..take it day to day...Boobetty