I agree Flip, I like the 10/650's the best also. I've never tried VP, too expensive right now but I really want to. When you take your break, do you use something in it's place? I use Ultram when I'm taking a break from the Hydro, it helps quite a bit.

Also, the comment above about taking the Hydro with a warm bev is a great suggestion. I typically take mine with a carbonated beverage, but coffee is great too. Not all can tolerate that without some food in the tummy though.