Hands Down- Didrex is by far the most effective for me. I lossed about 100 lbs within a year's time. However over the six months of not taking it I have re-gained 40 lbs!

I was never hungry while on Didrex. I had to remind myself to eat while taking it... to the point of I started taking vitamins to make up for poor eating habbits that developed while on Didrex. Didrex is not always easy to get though, sometimes it is out of stock.